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A pan-cancer signature of neutral tumor evolution

bioRxiv

Feb 11, 2015

Andrea Sottoriva, Trevor A. Graham

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Abstract

Despite extraordinary efforts to profile cancer genomes on a large scale, interpreting the vast amount of genomic data in the light of cancer evolution and in a clinically relevant manner remains challenging. Here we demonstrate that cancer next-generation sequencing data is dominated b...read more

Mentioned in this Paper

Mutant
Pan-neural Process
Gene Mutant
Mutation Abnormality
Genomic Stability
Genome
Tumor Growth
Evolution, Neutral
Neoplasms
Malignant Neoplasms
14
34
Paper Details
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  • A pan-cancer signature of neutral tumor evolution

    bioRxiv

    Feb 11, 2015

    Andrea Sottoriva, Trevor A. Graham

    PMID: 990014894

    DOI: 10.1101/014894

    Abstract

    Despite extraordinary efforts to profile cancer genomes on a large scale, interpreting the vast amount of genomic data in the light of cancer evolution and in a clinically relevant manner remains challenging. Here we demonstrate that cancer next-generation sequencing data is dominated b...read more

    Mentioned in this Paper

    Mutant
    Pan-neural Process
    Gene Mutant
    Mutation Abnormality
    Genomic Stability
    14
    34
    Paper Details
    References
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