A pancreatic zone at higher risk of fistula after enucleation

World Journal of Surgical Oncology
Pauline DuconseilOlivier Turrini

Abstract

To determine predictive factors of postoperative pancreatic fistula (POPF) in patients undergoing enucleation (EN). From 2005 to 2017, 47 patients underwent EN and had magnetic resonance imaging available for precise analysis of tumor location. Three pancreatic zones were delimited by the right side of the portal vein and the main pancreatic head duct (zone #3 comprising the lower head parenchyma and the uncinate process). The mortality and morbidity rates were 0% and 62%, respectively. POPF occurred in 23 patients (49%) and was graded as B or C (severe) in 15 patients (32%). Four patients (8.5%) developed a postoperative hemorrhage, and 5 patients (11%) needed a reintervention. In univariate and multivariate analyses, the pancreatic zone was the unique predictive factor of overall (P = .048) or severe POPF (P = .05). We did not observe any difference in postoperative courses when comparing the EN achieved in zones #1 and #2. We noted a longer operative duration (P = .016), higher overall (P = .017) and severe POPF (P = .01) rates, and longer hospital stays (P = .04) when comparing the EN achieved in zone #3 versus that in zones #1 and #2. Patients who underwent EN in zone #3 had a relative risk of developing a severe POPF of 3...Continue Reading

References

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Sep 9, 2017·Annals of Surgery·Olivier FargesAlain Sauvanet

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Citations

Aug 1, 2019·Surgical Endoscopy·Raffaele Dalla ValleMaurizio Iaria
May 1, 2021·Journal of Clinical Medicine·Ugo MarcheseDavid Fuks
Jun 13, 2021·Pancreatology : Official Journal of the International Association of Pancreatology (IAP) ... [et Al.]·Qiang XuYupei Zhao

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Methods Mentioned

BETA
pancreatectomies
pancreatectomy

Software Mentioned

SAS
GraphPad Prism
GraphPad

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