A paradoxical effect of bronchodilators

Chest
E MauryG Offenstadt

Abstract

Lactic acidosis previously has been reported during treatment of asthma with beta-2 agonists. However, this metabolic disturbance never had any clinical consequence. We report a case of a patient with asthma in whom beta-2 agonist administration increased dyspnea by metabolic acidosis due to a sharp increase in lactate levels (hyperlactatemia) and led to inappropriate intensification of bronchodilator therapy.

Associated Clinical Trials

Feb 27, 2014·Joseph Anthony Zitek, Joseph Anthony Zitek

References

Oct 3, 1985·The New England Journal of Medicine·G L BradenJ A Dawson
Oct 1, 1983·The American Journal of Medicine·D AppelM H Williams
May 1, 1983·American Journal of Obstetrics and Gynecology·S R RichardsL E Stempel

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Citations

Jan 2, 2007·European Journal of Emergency Medicine : Official Journal of the European Society for Emergency Medicine·Pulin B KoulBalagangadhar R Totapally
Oct 2, 2007·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Kathleen L MeertAshok P Sarnaik
Nov 9, 2007·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Desmond Bohn
Apr 5, 2011·Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies·Kathleen L MeertAshok P Sarnaik
Mar 22, 2006·Respirology : Official Journal of the Asian Pacific Society of Respirology·Antony E TobinJohn D Santamaria
May 25, 2005·Emergency Medicine Journal : EMJ·G J Rodrigo, C Rodrigo
May 17, 2012·Clinical Medicine : Journal of the Royal College of Physicians of London·Sharon Sturney, Jay Suntharalingam
Nov 6, 2010·Chest·Rahul K MishraKenneth M Nugent
Mar 10, 2004·Chest·Gustavo J RodrigoJesse B Hall
Jun 4, 2014·Chest·Lawrence M LewisKazuko Matsuda
Aug 2, 2011·The American Journal of Emergency Medicine·Pierre-Géraud ClaretJean-Emmanuel de la Coussaye
Jun 2, 2009·Anales de pediatría : publicación oficial de la Asociación Española de Pediatría (A.E.P.)·D González JiménezI García Hernández
Mar 14, 2007·Annales Françaises D'anesthèsie Et De Rèanimation·K ChaulierT Rimmelé
Sep 12, 2007·Anaesthesia·J Hulme
May 26, 2004·La Revue de médecine interne·A Du-ThanhA Le Quellec
Jul 13, 2002·Chest·Grigoris StratakosCharis Roussos
Oct 2, 2015·Pharmaceuticals·Joseph VamecqDries Dobbelaere
Aug 21, 2013·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Guillermo A RaimondiHoracio J Adrogué
Aug 1, 2015·Emergency Medicine Clinics of North America·Nathan B MenkeAndrew M King
Mar 2, 2005·Internal Medicine Journal·A Tobin, J Santamaria
Sep 25, 2018·Pediatrics International : Official Journal of the Japan Pediatric Society·Akinobu TaniguchiSeiji Hayashi
Jan 19, 2007·Acta Anaesthesiologica Scandinavica·M PytteN O Skaga
Jul 5, 2011·CJEM·Reid McGonigle, Robert A Woods
Jan 2, 2020·Journal of Clinical Medicine·Alina G LiedtkePietro B Faré

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