A Parallel Randomized Clinical Trial Examining the Return of Urinary Continence after Robot-Assisted Radical Prostatectomy with or without a Small Intestinal Submucosa Bladder Neck Sling

The Journal of Urology
Clinton D BahlerMichael O Koch

Abstract

Urinary continence is a driver of quality of life after radical prostatectomy. In this study we evaluated the impact of a biological bladder neck sling on the return of urinary continence after robot-assisted radical prostatectomy. This study compared early continence in patients undergoing robot-assisted radical prostatectomy with a sling and without a sling in a 2-group, 1:1, parallel, randomized controlled trial. Patients were blinded to group assignment. The primary outcome was defined as urinary continence (0 to 1 pad per day) at 1 month postoperatively. Inclusion criteria were organ confined prostate cancer and a prostate specific antigen less than 15 ng/ml. Exclusion criteria were any prior surgery on the prostate, a history of neurogenic bladder and history of pelvic radiation. A chi-squared test was used for the primary outcome. A total of 147 patients were randomized (control 74, sling 73) and 92% were available for primary end point analysis at 1 month. There were no significant differences in baseline or perioperative data except that operating room time was 20.1 minutes longer for the sling group (p=0.04). The continence rate was similar between the control and sling groups at 1 month (47.1% vs 55.2%, p=0.34) and 1...Continue Reading

References

Oct 5, 2001·The American Journal of Pathology·T R KyriakidesP Bornstein
May 29, 2003·The Journal of Urology·Mani MenonUNKNOWN VIP Team
Jun 1, 2005·Urology·J Stephen JonesRaymond R Rackley
Sep 20, 2011·Journal of Endourology·Carlos Nuñez-MoraJavier Angulo-Cuesta

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Citations

Apr 9, 2019·Minerva urologica e nefrologica = The Italian journal of urology and nephrology·Fabio ZattoniFabrizio Dal Moro

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