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A particle associated with the polyadenylate segment in mammalian messenger RNA

Proceedings of the National Academy of Sciences of the United States of America

Nov 1, 1972

S W Kwan, G Brawerman

PMID: 4508317

Abstract

A structure consisting of poly(A) complexed with other components is released from polysomes by ribonuclease treatment. The poly(A) complex has a sedimentation value of 12-15, while the corresponding sedimentation value for free poly(A) is 4. The complex does not appear to represent an ...read more

Mentioned in this Paper

Polyribosomes
Centrifugation, Density Gradient
Set of Polysomal Ribosomes
SDS-PAGE
Polynucleotides
Sarcoma 180
Poly U
Plasma Protein Binding Capacity
Poly A
Alkaline Ribonuclease
Paper Details
References
  • References15
  • Citations100
12
  • References15
  • Citations100
12345...

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A particle associated with the polyadenylate segment in mammalian messenger RNA

Proceedings of the National Academy of Sciences of the United States of America

Nov 1, 1972

S W Kwan, G Brawerman

PMID: 4508317

DOI:

Abstract

A structure consisting of poly(A) complexed with other components is released from polysomes by ribonuclease treatment. The poly(A) complex has a sedimentation value of 12-15, while the corresponding sedimentation value for free poly(A) is 4. The complex does not appear to represent an ...read more

Mentioned in this Paper

Polyribosomes
Centrifugation, Density Gradient
Set of Polysomal Ribosomes
SDS-PAGE
Polynucleotides
Sarcoma 180
Poly U
Plasma Protein Binding Capacity
Poly A
Alkaline Ribonuclease

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mRNA Degradation

Different mRNAs have different levels of stability. mRNA degradation is a complex process involving several degradation pathways, many of which utilize similar enzymes. Here is the latest research focusing on mRNA degradation.

Related Papers

Proceedings of the National Academy of Sciences of the United States of America

A protein of molecular weight 78,000 bound to the polyadenylate region of eukaryotic messenger RNAs

Proceedings of the National Academy of Sciences of the United States of AmericaMarch 1, 1973
G Blobel
Journal of Molecular Biology

Isolation of messenger ribonucleoproteins from mammalian cells

Journal of Molecular BiologyJune 25, 1974
U Lindberg, B Sundquist
Paper Details
References
  • References15
  • Citations100
12
  • References15
  • Citations100
12345...
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