A patent infarct-related artery is associated with reduced long-term mortality after percutaneous transluminal coronary angioplasty for postinfarction ischemia and an ejection fraction <50%

Circulation
F K WeltyJ E Muller

Abstract

Prognosis after myocardial infarction (MI) is influenced by the presence of post-MI ischemia and possibly the patency of the infarct-related artery. The purpose of this study was to compare long-term outcome (reinfarction and death) in patients with open versus closed coronary arteries after percutaneous transluminal coronary angioplasty performed for MI complicated by persistent ischemia. Between 1981 and 1989, 505 patients underwent percutaneous transluminal coronary angioplasty for post-MI ischemia at the Deaconess Hospital. Long-term incidence (mean follow-up, 34 months) of death, nonfatal reinfarction, repeated coronary angioplasty, and coronary bypass surgery was determined for 479 patients and then compared on the basis of the status of the artery, open versus closed, at the end of angioplasty. The 5-year Kaplan-Meier actuarial mortality rate was 4.9% for 456 patients with open infarct-related arteries and 19.4% for 23 patients with closed infarct-related arteries (P=.0008). Multivariate Cox proportional hazards analyses controlling for age, sex, number of diseased vessels, type and location of MI, and year of coronary angioplasty revealed a hazard ratio for death for closed compared with open arteries of 6.1 (95% CI, 1....Continue Reading

References

Dec 15, 1992·The American Journal of Cardiology·J D BoehrerL D Hillis
Apr 1, 1990·The American Journal of Cardiology·F AlfonsoP Zarco
Mar 1, 1987·Catheterization and Cardiovascular Diagnosis·S O GottliebJ A Brinker
Aug 1, 1988·The American Journal of Cardiology·J E DalenG Knatterud
Jun 1, 1974·British Heart Journal·N C ChaturvediJ M Barber
Dec 15, 1983·The New England Journal of Medicine·J W KennedyJ K Fritz
Oct 1, 1981·The American Journal of Cardiology·A MarmorR Roberts
Nov 5, 1981·The New England Journal of Medicine·E H Schuster, B H Bulkley
Mar 12, 1981·The New England Journal of Medicine·D E SingerG O Barnett
Jan 1, 1994·Journal of the American College of Cardiology·F K WeltyS J Shubrooks
Jul 1, 1955·A.M.A. Archives of Internal Medicine·N W McQUAYH B BURCHELL

❮ Previous
Next ❯

Citations

Mar 15, 2000·Journal of the American College of Cardiology·K H Mak, E J Topol
Mar 26, 2005·Circulation Journal : Official Journal of the Japanese Circulation Society·Takahiro HayashiKinji Ishikawa
Feb 13, 2013·Interactive Cardiovascular and Thoracic Surgery·Sevket BaltaSait Demirkol
Jul 24, 2007·Heart Failure Clinics·George M ComasMehmet C Oz
Mar 14, 2007·International Journal of Cardiology·Nipon ChattipakornSiriporn Chattipakorn
Jun 28, 2000·Progress in Cardiovascular Diseases·L Carnendran, J S Steinberg
Oct 20, 1998·American Heart Journal·I C HsiehD Wu
Apr 30, 1998·Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography·M L MainP A Grayburn

❮ Previous
Next ❯