A peculiar case of large primary cutaneous Ewing's sarcoma of the foot: Case report and review of the literature

International Journal of Surgery Case Reports
Luca GrassettiGiovanni Di Benedetto

Abstract

Primary cutaneous extraskeletal Ewing's sarcomas (ESs) are extremely rare tumors, limited to the skin and generally appear as a single small lesion, circumscribed mid-to-deep dermis or involving subcutis. Due to their rarity and morphological similarity to other cutaneous tumors, ESs are subject to being clinically and pathologically subdiagnosed. A 37-year-old man presented a large rapidly growing mass of the first toe measuring 9.5×8cm with no radiological evidence of bone involvement. The patient underwent wide surgical tumor resection; histological, immunohistochemical and molecular evaluation confirmed the diagnosis of ESs. Postoperative examinations revealed no metastasis and after 11 months follow-up no recurrences were detected. Current literature reports only a few isolated cases or small series. ESs are generally described as small masses with a favorable clinical behavior. Despite lower extremity is a relatively frequent site, only rare and small ESs of the foot have been reported. To our knowledge the present case is the largest ES of the foot. Despite its large size, the patient did not report any metastases confirming the hypothesis of treating superficial ES with surgery alone, thus avoiding adjuvant radiotherapy...Continue Reading

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Citations

Mar 5, 2016·International Journal of Dermatology·Morgane BarreauAnne Dompmartin
Nov 9, 2020·Actas dermo-sifiliográficas·M PosadaH Sarti

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Methods Mentioned

BETA
surgical resection
amputation
periodic acid Shiff

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