A peptide action in a lobster neuromuscular preparation

Journal of Neurobiology
T L SchwarzE A Kravitz

Abstract

The neuropeptide proctolin causes a sustained contraction of the opener muscle of the dactyl of the lobster walking leg. This substance acts directly on the muscle at concentrations as low as 10(-10)M. The contraction is dependent on extracellular calcium. Neither a significant depolarization nor a detectable change in the input resistance accompanies the response. No presynaptic action of proctolin is indicated; excitatory and inhibitory junctional potential sizes and the frequency of spontaneous miniature excitatory junctional potentials are unaffected.

References

Oct 15, 1975·Life Sciences·B E Brown
Oct 1, 1966·Proceedings of the National Academy of Sciences of the United States of America·M OtsukaE A Kravitz
Mar 1, 1964·The Journal of Physiology·A TAKEUCHI, N TAKEUCHI
Apr 4, 1980·Science·M S LivingstoneE A Kravitz

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Citations

Jan 1, 1989·Pharmacology & Therapeutics·G A Cottrell, G S Bewick
Jan 1, 1985·Peptides·K K SiwickiE A Kravitz
Jan 1, 1982·Comparative Biochemistry and Physiology. C: Comparative Pharmacology·R J Walker, C J Roberts
Jan 1, 1985·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·J Nwoga, E E Bittar
Jan 1, 1985·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·B J Cook, G M Holman
Sep 1, 1981·Proceedings of the National Academy of Sciences of the United States of America·C A BishopR J Miller
Aug 21, 2010·Cellular and Molecular Life Sciences : CMLS·Andrew E ChristiePatsy S Dickinson
Jul 1, 1989·Journal of Neurobiology·I OrchardA B Lange
Nov 6, 2015·Journal of Neurophysiology·Kiel G OrmerodA Joffre Mercier
Jan 21, 2006·The Journal of Experimental Biology·Berit PhilippSabine Kreissl
Feb 6, 1984·Life Sciences·G B QuistadD A Schooley
Jan 22, 1986·The Journal of Comparative Neurology·K K Siwicki, C A Bishop
Feb 15, 1985·The Journal of Comparative Neurology·C Li, R L Calabrese
Sep 1, 1985·Journal of Neurobiology·A J Mercier, J L Wilkens
May 1, 1984·Journal of Neurobiology·S G RaneG A Wyse

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