A peptide domain of bovine milk lactoferrin inhibits the interaction between streptococcal surface protein antigen and a salivary agglutinin peptide domain

Infection and Immunity
Takahiko OhoJ Groenink

Abstract

The peptide domain of salivary agglutinin responsible for its interaction with cell surface protein antigen (PAc) of Streptococcus mutans or bovine lactoferrin was found in the same peptide, scavenger receptor cysteine-rich domain peptide 2 (SRCRP2). Inhibition studies suggest that PAc and lactoferrin, of which residues 480 to 492 seem important, competitively bind to the SRCRP2 domain of salivary agglutinin.

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Citations

Jan 1, 2010·International Journal of Molecular Sciences·Antoon J M LigtenbergEnno C I Veerman
Mar 26, 2016·Frontiers in Immunology·Martin Parnov Reichhardt, Seppo Meri
Apr 27, 2010·Innate Immunity·Jens MadsenUffe Holmskov
Mar 13, 2019·Molecular Oral Microbiology·Takahiko Oho, Emi Nagata
Mar 5, 2021·Journal of Oral Biosciences·Anna M Krupińska, Zdzisław Bogucki
Jul 3, 2017·Molecular Immunology·M P ReichhardtS Meri

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