A perinatal stress calculator for the neonatal intensive care unit: an unobtrusive approach.

Physiological Measurement
M LavangaA Caicedo

Abstract

Early experience of pain and stress in the neonatal intensive care unit is known to have an effect on the neurodevelopment of the infant. However, an automated method to quantify the procedural pain or perinatal stress in premature patients does not exist. In the current study, EEG and ECG data were collected for more than 3 hours from 136 patients in order to quantify stress exposure. Specifically, features extracted from the EEG and heart-rate variability in both quiet and non-quiet sleep segments were used to develop a subspace linear-discriminant analysis stress classifier. The main novelty of the study lies in the absence of intrusive methods or pain elicitation protocols to develop the stress classifier. Three main findings can be reported. First, we developed different stress classifiers for the different age groups and stress intensities, obtaining an area under the curve in the range [0.78-0.93] for non-quiet sleep and [0.77-0.96] for quiet sleep. Second, a dysmature EEG was found in patients under stress. Third, an enhanced cortical connectivity and increased brain-heart communication was correlated with a higher stress load, while the autonomic activity did not seem to be associated to stress exposure. The results sh...Continue Reading

References

May 15, 2002·Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics·Michael G RosenblumRalf Mrowka
Aug 20, 2002·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Douglas E LakeJ Randall Moorman
Aug 23, 2002·Physical Review Letters·Madalena CostaC-K Peng
Apr 19, 2003·European Journal of Clinical Pharmacology·Karel AllegaertHugo Devlieger
Sep 8, 2004·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Guido NolteMark Hallett
Dec 13, 2005·Biological cybernetics·D PopivanovS Kosev
Nov 11, 2006·Journal of Applied Physiology·Maya DavidSolange Akselrod
Oct 2, 2007·Seminars in Perinatology·Manon RangerK J S Anand
Apr 29, 2008·Neuroscience Letters·Klaus PfurtschellerGert Pfurtscheller
Feb 5, 2009·Nature Reviews. Neuroscience·Ed Bullmore, Olaf Sporns
Jun 2, 2009·European Journal of Pain : EJP·Rebeccah SlaterMaria Fitzgerald
Jun 1, 2010·Neurophysiologie clinique = Clinical neurophysiology·M AndréP Plouin
Jun 1, 2010·Neurophysiologie clinique = Clinical neurophysiology·F Wallois
Nov 3, 2010·American Journal of Physiology. Heart and Circulatory Physiology·Douglas E Lake, J Randall Moorman
Nov 16, 2010·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Julián J GonzálezErnesto Pereda
Nov 26, 2010·Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society·P AbryM Doret
Oct 25, 2011·Neuroscience and Biobehavioral Reviews·Gennady G Knyazev
Mar 1, 2012·Annals of Neurology·Susanne BrummelteSteven P Miller
May 19, 2012·The Journal of Pain : Official Journal of the American Pain Society·Xiaomei CongDi Zhang
Nov 23, 2012·Paediatric Anaesthesia·Karel AllegaertBrian J Anderson
Nov 15, 2013·Rambam Maimonides Medical Journal·Ruth Eckstein Grunau
Mar 24, 2015·Physiological Measurement·L FaesG Nollo
Dec 5, 2015·Frontiers in Human Neuroscience·Marina de TommasoSebastiano Stramaglia
Jun 16, 2016·IEEE Transactions on Bio-medical Engineering·Karin SchieckeHerbert Witte
Jun 28, 2016·Scientific Reports·Lorenzo FabriziMaria Fitzgerald
Oct 27, 2016·Neuroscience·Madeleine VerriotisLorenzo Fabrizi
Dec 3, 2016·Journal of Neurophysiology·Gaurav MisraStephen A Coombes
Dec 3, 2016·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Gert PfurtschellerAlexandre Andrade
Apr 14, 2017·Developmental Neuroscience·Elena PavlidisGeraldine B Boylan
Jul 18, 2017·Early Human Development·Anneleen DereymaekerGunnar Naulaers
Aug 5, 2017·Circulation Research·Zhili ChenJieli Chen
Sep 28, 2017·IEEE Transactions on Bio-medical Engineering·Vishal VijayakumarBin He
Oct 21, 2017·Children·Daphna Yasova Barbeau, Michael D Weiss
Dec 20, 2017·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Emma G DuerdenSteven P Miller
Jan 31, 2018·Journal of Neural Engineering·Kirubin PillayMaarten De Vos
Mar 30, 2018·Physiological Measurement·M LavangaS Van Huffel

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