A personalized intervention to prevent depression in primary care: cost-effectiveness study nested into a clustered randomized trial

BMC Medicine
Anna FernándezJuan Ángel Bellón

Abstract

Depression is viewed as a major and increasing public health issue, as it causes high distress in the people experiencing it and considerable financial costs to society. Efforts are being made to reduce this burden by preventing depression. A critical component of this strategy is the ability to assess the individual level and profile of risk for the development of major depression. This paper presents the cost-effectiveness of a personalized intervention based on the risk of developing depression carried out in primary care, compared with usual care. Cost-effectiveness analyses are nested within a multicentre, clustered, randomized controlled trial of a personalized intervention to prevent depression. The study was carried out in 70 primary care centres from seven cities in Spain. Two general practitioners (GPs) were randomly sampled from those prepared to participate in each centre (i.e. 140 GPs), and 3326 participants consented and were eligible to participate. The intervention included the GP communicating to the patient his/her individual risk for depression and personal risk factors and the construction by both GPs and patients of a psychosocial programme tailored to prevent depression. In addition, GPs carried out measur...Continue Reading

References

Mar 17, 2001·Health Economics·A H Briggs, B J O'Brien
Jul 13, 2002·Gaceta sanitaria·J A SacristánJ L Pinto
Sep 10, 2002·Medical Care·Martin L LeeLisa V Rubenstein
Mar 11, 2003·Journal of Occupational and Environmental Medicine·Ronald C KesslerPhillip Wang
Nov 15, 2003·BMJ : British Medical Journal·Bruce ArrollNgaire Kerse
Jun 3, 2004·The British Journal of Psychiatry : the Journal of Mental Science·Gavin AndrewsHelen Lapsley
Aug 2, 2005·The British Journal of Psychiatry : the Journal of Mental Science·Elisabeth Fenwick, Sarah Byford
Feb 25, 2006·Health Economics·David Parkin, Nancy Devlin
Feb 20, 2008·Annals of Internal Medicine·Isabelle BoutronUNKNOWN CONSORT Group
Aug 4, 2010·Health Affairs·Jeffrey BorkanAlejandro R Jadad
Sep 20, 2011·European Neuropsychopharmacology : the Journal of the European College of Neuropsychopharmacology·Anders GustavssonUNKNOWN CDBE2010Study Group
Oct 22, 2011·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Manuel GomesSimon G Thompson
Jun 27, 2013·The Australian and New Zealand Journal of Psychiatry·Felice N JackaMichael Berk
Apr 25, 2014·International Journal of Epidemiology·Kim van ZoonenPim Cuijpers
Jun 26, 2014·Early Intervention in Psychiatry·Cathrine Mihalopoulos, Mary Lou Chatterton
Aug 28, 2014·The New England Journal of Medicine·Peter J NeumannMilton C Weinstein
Mar 5, 2015·The New England Journal of Medicine·Martin Marshall
Mar 29, 2016·Annals of Internal Medicine·Juan Ángel BellónJuan de Dios Luna

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Citations

Sep 24, 2020·Health Economics Review·Juliane Andrea DuevelWolfgang Greiner
Jan 27, 2021·The British Journal of General Practice : the Journal of the Royal College of General Practitioners·Patricia Moreno-PeralJuan Ángel Bellón
Jul 26, 2021·Clinical Psychology Review·Sonia Conejo-CerónJuan Ángel Bellón

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