PMID: 3760894Sep 1, 1986Paper

A pharmacodynamic evaluation of midazolam as an antiepileptic compound

Journal of Neurology, Neurosurgery, and Psychiatry
S JawadA Richens

Abstract

Midazolam is a water soluble 1,4 benzodiazepine which is suitable for intramuscular administration. It is currently used for pre-medication and the induction of anaesthesia. Its antiepileptic properties have been evaluated by studying its effect on interictal spikes on the EEG of six adult epileptic patients. The results indicate that intramuscular midazolam 15 mg is more effective than intramuscular diazepam 10 mg in abolishing interictal spikes and as effective as intravenous diazepam 20 mg five minutes after administration.

References

Jan 1, 1978·Anesthesia and Analgesia·J T ConnerC W Graham
Jan 1, 1983·British Journal of Clinical Pharmacology·M Gerecke
Jan 1, 1983·British Journal of Clinical Pharmacology·L Pieri
Sep 1, 1983·British Journal of Clinical Pharmacology·N MilliganA Richens
May 1, 1981·British Journal of Clinical Pharmacology·N Milligan, A Richens
Aug 1, 1976·British Journal of Clinical Pharmacology·S AhmadA Richens

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Citations

Dec 1, 1993·Electroencephalography and Clinical Neurophysiology·L A KearseK McPeck
May 1, 1992·Pediatric Neurology·E LahatY Katz
Jan 23, 1999·Clinical Therapeutics·D F Hanley, J F Kross
Mar 1, 1997·Annals of Emergency Medicine·J L KendallR Goldberg
Apr 9, 1999·The Journal of Emergency Medicine·A R Towne, R J DeLorenzo
May 18, 1999·Pediatric Neurology·G L Holmes, J J Riviello
May 1, 1988·Journal of Neurology, Neurosurgery, and Psychiatry·S GhilainT H de Barsy
Apr 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·B A Wroblewski, A B Joseph
Feb 1, 1993·Journal of Neurology, Neurosurgery, and Psychiatry·S Shorvon
Mar 1, 2012·International Journal of Clinical Pharmacology and Therapeutics·Michael Bewernitz, Hartmut Derendorf
Aug 6, 2013·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·S RamppH Stefan
Jan 1, 1991·Intensive Care Medicine·R Ritz
Jun 17, 2004·Drug and Chemical Toxicology·Benedict R CapacioJ H McDonough
Mar 11, 2008·Epilepsia·Daniel H Lowenstein, James Cloyd
May 1, 1994·The American Journal of Emergency Medicine·S L Orebaugh, S M Bradford
Aug 1, 1986·British Journal of Clinical Pharmacology·S JawadA Richens
Jul 6, 2005·Journal of Child Neurology·Judith C D BrevoordMatthijs de Hoog
Feb 24, 2001·Journal of Child Neurology·T FişginD Akgün
Aug 31, 2018·Epilepsia·Patricia D MaglalangJames C Cloyd
Apr 1, 1992·Journal of Neurology, Neurosurgery, and Psychiatry·A I BhigjeeI M Windsor
Aug 29, 2019·Epilepsy Currents·Edward Faught

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