PMID: 2492203Feb 1, 1989Paper

A phase I study of hepatic arterial infusion using difluoromethylornithine

Cancer
A LiptonJ L Barlow

Abstract

Ten patients with metastatic disease to the liver were treated with difluoromethylornithine (DFMO) administered by continuous hepatic arterial infusion. Two of nine evaluable patients had an objective partial response. Stable disease was recorded in three patients. Ototoxicity was encountered in all patients who received a daily dose of DFMO equal to or greater than 1.0 g/m2.

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Citations

Aug 1, 1991·Annals of Medicine·J JänneP Leinonen
Mar 17, 2001·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·L I ShotlandJ L Viner

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