PMID: 3759564Aug 1, 1986Paper

A phase II study of CCNU with benznidazole for metastatic malignant melanoma

International Journal of Radiation Oncology, Biology, Physics
N M BleehenH F Newman

Abstract

The response of 18 patients with metastatic malignant melanoma to the combination of CCNU (130 mg/m2) preceded 3-4 hr earlier by 20 mg/kg of the 2-nitroimidazole benznidazole has been studied. There were four partial and no complete responses in 16 patients evaluable after 1-6 courses. The median response duration was 14 wk (range 5-33) and for static disease 24 wk (range 10-54). Evidence for chemosensitization is equivocal.

References

Dec 1, 1987·The American Journal of Surgical Pathology·P L FitzgibbonsT J Simmons
Feb 1, 1985·International Journal of Radiation Oncology, Biology, Physics·J T Roberts, N M Bleehen
Sep 1, 1984·International Journal of Radiation Oncology, Biology, Physics·D W Siemann
Sep 1, 1984·International Journal of Radiation Oncology, Biology, Physics·J T RobertsM I Walton
Dec 1, 1982·Nursing Mirror
Mar 1, 1982·International Journal of Radiation Oncology, Biology, Physics·J M Brown

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Citations

Mar 1, 1989·Cancer Treatment Reviews·D J Stewart, W K Evans
Oct 28, 2016·Cancer Biology & Therapy·Quhuan LiZhong Yun
May 1, 1995·International Journal of Hyperthermia : the Official Journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group·D J Chaplin

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