A phosphinate-based near-infrared fluorescence probe for imaging the superoxide radical anion in vitro and in vivo

Chemical Communications : Chem Comm
Jianjian ZhangHaixia Zhang

Abstract

A novel near-infrared (NIR), turn-on fluorescence probe containing a phosphinate group as a recognizing moiety for the selective detection of O2˙(-) with a low limit of detection (LOD, 9.9 nM) was developed. has good cell-membrane permeability, intracellular stability, and low cytotoxicity. In addition, we successfully applied the to visualize O2˙(-) in live zebrafish, mouse and, for the first time, in mouse liver.

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Citations

Mar 4, 2017·Chemistry : a European Journal·Diana AndinaPaola Luciani
Jan 10, 2018·Angewandte Chemie·Qingqing MiaoKanyi Pu
Aug 25, 2017·Chemical Communications : Chem Comm·Zuo Hang YuHo Yu Au-Yeung
Feb 16, 2019·Scientific Reports·Ying WangLina Cui
Oct 27, 2017·Current Medicinal Chemistry·Hai-Yan WangYi Liu
Apr 3, 2020·ChemPlusChem·Fung Kit TangHo Yu Au-Yeung
Mar 14, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Qiuyun YangQi Zhang
Apr 14, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Jianhua MaXiaojun Peng
Jan 2, 2021·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Eli M EspinozaNiren Murthy

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