A phytochemical study of the Cuphea glutinosa from Southern Brazil: Na+ ,K+ -ATPase activity inhibition and antioxidant properties

Natural Product Research
Adriana M ZagoAdemir F Morel

Abstract

This study investigated the antioxidant activity of Cuphea glutinosa (CG) and its effect on Na+, K+-ATPase from cardiac muscle. The ethanolic extract showed higher antioxidant capacity compared to aqueous and ethyl acetate fraction. Ethyl acetate fraction showed β-sitosterol-3-O-β-glucoside, kaempferol, quercetin, isoquercetin, gallic acid methyl ester, and gallic acid. The ethanolic extract also reduced the Na+,K+-ATPase activity. CG presented a promising antioxidant activity and inhibitory effect on the Na+, K+-ATPase activity, supporting biochemical evidences the popular use of this plant in the treatment of heart failure.

References

Feb 11, 1988·The New England Journal of Medicine·T W Smith
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Jun 5, 2002·Annual Review of Biochemistry·Jack H Kaplan
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Jun 19, 2013·Journal of Molecular and Cellular Cardiology·J M AronsenO M Sejersted

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Citations

Apr 21, 2020·Natural Product Research·Loan Ngoc Phuong NguyenPhu Hoang Dang

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Methods Mentioned

BETA
NMR
MDA

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