A pilot exercise intervention to improve lower extremity functioning in peripheral arterial disease unaccompanied by intermittent claudication

Journal of Cardiopulmonary Rehabilitation
Mary M McDermottLuigi Ferrucci

Abstract

A pilot study was conducted to test the feasibility of supervised treadmill exercise training to improve functioning in study participants with peripheral arterial disease who did not have classical symptoms of intermittent claudication. For this study, 32 men and women with peripheral arterial disease but no symptoms of claudication were randomized to exercise training or usual care. The intervention was a 12-week supervised treadmill walking program. Outcomes included 6-minute walk distance, maximum treadmill walking distance, and 4-meter walking velocity. Participant-reported community walking ability was measured with the Walking Impairment Questionnaire (WIQ). Inflammatory blood factor levels also were measured. Altogether, 25 participants who completed follow-up testing were included in intention-to-treat analyses. Of 24 participants (58%) randomized to exercise, 14 completed the entire exercise training program. The participants randomized to the intervention showed greater improvement in their WIQ walking speed score than the control subjects (P =.05). The participants randomized to the intervention showed improvements in their 6-minute walk distance (1134 +/- 347 vs 1266 +/- 295 feet; P =.03), maximal treadmill walking...Continue Reading

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Citations

Jul 3, 2007·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Heather K VincentAnn G Taylor
Jan 16, 2016·Rehabilitation Research and Practice·Sara A MyersJason M Johanning
Dec 6, 2005·Journal of Vascular Nursing : Official Publication of the Society for Peripheral Vascular Nursing·Roberta K OkaJohn P Cooke
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Apr 9, 2018·The Cochrane Database of Systematic Reviews·David HagemanJoep Aw Teijink
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Aug 24, 2013·The Cochrane Database of Systematic Reviews·Hugo J P FokkenroodJoep A W Teijink
Sep 13, 2006·The Journal of Cardiovascular Nursing·Roberta K Oka

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