A pilot investigation of the effect of electronic cigarettes on smoking behavior among opioid-dependent smokers

Addictive Behaviors
Nicholas J FelicioneMelissa D Blank

Abstract

Compared to the general population, smoking rates are 2-4 times higher among individuals with opioid use disorders (OUDs). These smokers also have poor long-term cessation rates, even with pharmacotherapy or other interventions. Low success rates with traditional approaches may prompt smokers with OUDs to try more novel products like electronic cigarettes (ECIGs). This pilot study was designed to examine the feasibility, acceptability, and effect of ECIGs on smoking behavior among smokers with OUD. Participants (N = 25) were daily smokers receiving buprenorphine/naloxone for OUD at an outpatient clinic. They were randomized to use a second-generation ECIG (0 or 18 ng/ml nicotine) ad libitum for two weeks while completing assessments via text messaging daily, and also via in-person visits at baseline, end of the two-week intervention, and a 4-week follow-up. Feasibility was evidenced by high enrollment (93.9%) and retention (70.9%) rates. ECIG adherence was relatively high as measured by self-report (80.6% active, 91.7% placebo), while the average volume of liquid used per week was low (~3 ml). Both ECIG doses produced reductions in self-reported cigarettes per day that were not supported by average carbon monoxide levels. Biolo...Continue Reading

Citations

Feb 29, 2020·CNS Drugs·Cynthia VladShadi Nahvi
Aug 10, 2020·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Billie BonevskiDan I Lubman
Apr 30, 2021·The Cochrane Database of Systematic Reviews·Jamie Hartmann-BoycePeter Hajek
Oct 15, 2020·The Cochrane Database of Systematic Reviews·Jamie Hartmann-BoycePeter Hajek
Sep 15, 2021·The Cochrane Database of Systematic Reviews·Jamie Hartmann-BoycePeter Hajek
Dec 17, 2021·Nicotine & Tobacco Research : Official Journal of the Society for Research on Nicotine and Tobacco·Joanna M StreckNancy A Rigotti
Sep 8, 2021·Substance Abuse : Official Publication of the Association for Medical Education and Research in Substance Abuse·Jenny E OzgaRobin A Pollini

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