A pilot randomised controlled trial of a home-based exercise programme aimed at improving endurance and function in adults with neuromuscular disorders.

Journal of Neurology, Neurosurgery, and Psychiatry
H DawesD H Jones

Abstract

To investigate the feasibility and effect of a home-based exercise programme on walking endurance, muscle strength, fatigue and function in people with neuromuscular disorders (NMDs). 20 adults with NMDs recruited to a control (n = 11) or exercise (n = 9) group were assessed by blinded assessors at baseline and at week 8. Walking and strengthening exercises were given to the exercise group in an 8-week home exercise programme. A 2-min walk distance was the main outcome measurement; isometric muscle strength, fatigue and function were secondary measurements. 2-min walk distances were not found to change in either group (p>0.05; control: mean 14.50 (SD 22.06) m; exercise: mean 2.88 (SD 20.08) m), and no difference was observed in the change scores between groups (p>0.05). Leg muscle strength increased in the exercise group (p<0.05) but not in the control group (p>0.05). Significance was reached between the groups with respect to the difference in change in muscle strength scores in the right quadriceps (p<0.05; control: mean -2.82 (SD 4.87) kg; exercise: mean -7.08 (SD 2.82) kg). No change was observed in fatigue or function scores (p<0.05). A home-based approach aimed at improving endurance in adults with NMDs is feasible and fu...Continue Reading

References

Feb 1, 1993·Journal of Clinical Epidemiology·R A WashburnC A Janney
Jan 9, 1998·Archives of Physical Medicine and Rehabilitation·D D KilmerS G Aitkens
Nov 1, 2002·American Journal of Physical Medicine & Rehabilitation·David D Kilmer
Feb 10, 2004·Medicine and Science in Sports and Exercise·Elizabeth V CyartoCatrine Tudor-Locke
Feb 18, 2004·Archives of Physical Medicine and Rehabilitation·Louisa S DeBolt, Jeffrey A McCubbin
Jun 19, 2004·Disability and Rehabilitation·Mayra Santiago, Catherine Coyle
Jan 28, 2005·The Cochrane Database of Systematic Reviews·E L van der KooiI Riphagen

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Citations

Sep 11, 2012·Brain : a Journal of Neurology·Rudolf A KleyDieter O Fürst
Feb 11, 2014·American Journal of Physical Medicine & Rehabilitation·Gavin WilliamsAlana Randall
Dec 11, 2013·Translational Stroke Research·Rodrigo Daminello RaimundoMonica Akemi Sato
Feb 2, 2016·Scandinavian Journal of Primary Health Care·Sissel SteihaugAnne Werner
Oct 30, 2007·Archives of Physical Medicine and Rehabilitation·Edith H CupRob A Oostendorp
Nov 27, 2010·Physiotherapy Research International : the Journal for Researchers and Clinicians in Physical Therapy·Kjellaug OygardLone Jørgensen
May 6, 2010·Clinical Rehabilitation·Gita M Ramdharry
Feb 19, 2010·The Cochrane Database of Systematic Reviews·Kristy J RoseKathryn N North
Jul 10, 2013·The Cochrane Database of Systematic Reviews·Nicoline B M VoetAlexander C H Geurts
Dec 7, 2019·The Cochrane Database of Systematic Reviews·Nicoline Bm VoetAlexander Ch Geurts
May 4, 2018·Orphanet Journal of Rare Diseases·Oksana PogoryelovaAndreas Roos

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