PMID: 18203070Jan 19, 2008Paper

A pilot randomized controlled comparison of extended daily dialysis with filtration and continuous veno-venous hemofiltration: fluid removal and hemodynamics

The International Journal of Artificial Organs
Ian BaldwinNigel Fealy

Abstract

Extended intermittent dialytic techniques are increasingly being reported in the treatment of ARF in the ICU but few randomized controlled trials exist. We compared one such technique to a technique of continuous renal replacement therapy with regard to fluid removal and hemodynamics. Sixteen critically ill patients with ARF were enrolled in a randomized controlled trial at the ICU of a tertiary hospital. We randomized eight patients to three consecutive days of treatment with either Extended Daily Dialysis with filtration (EDDf) or Continuous Veno-Venous Hemofiltration (CVVH) and compared fluid removal and hemodynamics during treatment. A total of 16.6 liters of fluid were removed during EDDf (830 mL/day over 20 treatment days) compared with 15.4 liters (700 ml/day over 22 treatment days) during CVVH. Median fluid removal per day was 1837 mL in the EDDf group compared with 1410 mL per day in the CVVH group, p=0.674. Median hourly fluid removal rate was 252 mL for EDDf and 128 mL for CVVH (p<0.01). Mean arterial pressure in the EDDf group was lower at two hours after starting treatment (76 mmHg vs. 94 mmHg) in the CVVH group; p= 0.031. There was no significant difference between groups for heart rate, CVP and noradrenaline dose...Continue Reading

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Citations

Feb 6, 2013·Therapeutic Apheresis and Dialysis : Official Peer-reviewed Journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy·La-Ping ChuWen-Xia Dong
May 12, 2009·Seminars in Dialysis·Michael Joannidis
Oct 27, 2015·International Journal of Clinical Pharmacy·Jian P MeiBruce A Mueller
Jul 25, 2018·Clinical and Experimental Nephrology·Kent DoiUNKNOWN Japanese Clinical Practice Guideline for Acute Kidney Injury 2016 Committee
Aug 21, 2018·Journal of Intensive Care·Kent DoiUNKNOWN Japanese Clinical Practice Guideline for Acute Kidney Injury 2016 Committee
Nov 26, 2010·BMC Nephrology·Heather E FieghenUNKNOWN University of Toronto Acute Kidney Injury Research Group
Sep 27, 2013·Cell Biochemistry and Biophysics·Junzhang ChengRong Chen
Dec 19, 2018·The Cochrane Database of Systematic Reviews·Alicia Isabel I FayadAgustín Ciapponi
Feb 6, 2017·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Shakti Bedanta MishraMohan Gurjar
Jun 7, 2017·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Shakti Bedanta MishraArvind Kumar Baronia
Mar 13, 2021·Indian Journal of Critical Care Medicine : Peer-reviewed, Official Publication of Indian Society of Critical Care Medicine·Akila RajakumarMohamed Rela
Sep 15, 2021·The Cochrane Database of Systematic Reviews·Yasushi TsujimotoTomoko Fujii

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