A Pilot Study of Short-Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine in Patients with Diabetic Foot Ulcer Wagner 3-4

TheScientificWorldJournal
Hendry IrawanI Gde Raka Widiana

Abstract

To evaluate the short-duration hyperbaric oxygen therapy (HBOT) can improve HbA1c levels, leukocyte count, and serum creatinine levels in patients with diabetic foot ulcer (DFU) Wagner 3-4. Blood samples from all DFU patients at Sanglah General Hospital, Denpasar, were taken for HbA1c, leukocyte, and serum creatinine test before debridement procedure, and the patients were then grouped into either standard therapy or standard therapy with HBOT for 10 sessions (combination therapy). At the end of therapy, all blood tests were resumed. Each group consisted of 15 patients. Results of laboratory analysis before and after treatment were significant regarding decrease of HbA1c levels in standard therapy (10.98 ± 2.37 % to 9.70 ± 2.46 %; p = 0.006), HbA1c levels in combination therapy (9.42 ± 1.96 % to 7.07 ± 1.16 %; p < 0.001), and leukocyte count in combination therapy (13.97 ± 6.24 x 103 cells/μL to 8.84 ± 2.88 x 103 cells/μL; p = 0.009). The HbA1c levels at the end of therapy were significantly different between groups (p = 0.001). Serum creatinine level was decreased only in combination therapy but it was not significant. The effect size of all variables was larger in the combination therapy, but it was not significant (p > 0.05)...Continue Reading

References

Dec 29, 2006·Urologia Internationalis·Emrullah SolmazgulSenol Yildiz
Feb 7, 2007·The Journal of Foot and Ankle Surgery : Official Publication of the American College of Foot and Ankle Surgeons·Robert G FrykbergUNKNOWN American College of Foot and Ankle Surgeons
Apr 11, 2007·British Journal of Hospital Medicine·Dipanjan Banerjee, Ware G Kuschner
Jun 1, 2007·Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society·Caroline E FifeRobert Warriner
Sep 19, 2008·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Irit RubinsteinOri S Better
Jan 14, 2011·Plastic and Reconstructive Surgery·Stephen R Thom
Jan 25, 2012·Diabetic Medicine : a Journal of the British Diabetic Association·D WilkinsonL K Heilbronn
Nov 20, 2012·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Sourabh Bhutani, Guruswamy Vishwanath
May 15, 2013·Journal of Diabetes Research·Figen AydinMustafa Incesu
Jul 9, 2013·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·William J Jeffcoate, Frances L Game
Jul 12, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Dariusz WaniczekEwa Nowakowska-Zajdel
Mar 19, 2014·The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology·Varun Parkash SinghAmteshwar Singh Jaggi
Sep 2, 2014·TheScientificWorldJournal·Matitiahu BerkovitchIbrahim Abu-Kishk
Jan 17, 2015·Indian Journal of Plastic Surgery : Official Publication of the Association of Plastic Surgeons of India·Kenneth C Klein, Somes Chandra Guha

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Citations

Jul 26, 2019·Current Opinion in Anaesthesiology·Michael H Bennett, Simon J Mitchell
Jul 9, 2020·Angiology·Ivana ResanovićEsma R Isenović
Jul 5, 2019·Current Pharmaceutical Design·Silvia TejadaAntoni Sureda
Aug 18, 2020·Oxidative Medicine and Cellular Longevity·Jarosław PaprockiAlina Woźniak
Aug 28, 2021·Biomolecules·Silke D De WoldeRobert A Van Hulst

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