A Pilot Study on Feasibility and Effectiveness of Intraoperative Spectral-Domain Optical Coherence Tomography in Glaucoma Procedures

Translational Vision Science & Technology
Rajesh S KumarRohit Shetty

Abstract

To demonstrate the use of a spectral-domain optical coherence tomography (SDOCT) integrated surgical microscope in glaucoma surgery. An SDOCT system was used to interface directly with an ophthalmic surgical microscope, to allow real-time intraoperative SDOCT (iOCT) imaging during glaucoma procedures like phaco-trabeculectomy, Ahmed glaucoma valve (AGV) implantation, gonio-synechiolysis, and bleb needling. The various surgical steps during glaucoma surgeries where iOCT can be of potential help in guiding the surgeon were recorded. High-resolution, cross-sectional images of the relevant structures were achieved with the iOCT system in all procedures. The surgeon could determine the depth of the scleral dissection, the intrastomal bed, the path of the AGV tube in the eye, the release of peripheral anterior synechiae and the efficacy of needling with respect to breakage of loculations; most of these are technically 'blind' procedures, where the outcomes are determined postoperatively. Metallic instruments cast a shadow on tissues below, thereby restricting the use of the device in its current state. The iOCT system provided high quality, intraoperative, real-time imaging, which could possibly improve the safety and efficacy of the...Continue Reading

References

Dec 14, 2005·Archives of Ophthalmology·Teresa C ChenJohannes F de Boer
Aug 19, 2007·Clinical & Experimental Optometry : Journal of the Australian Optometrical Association·Jennifer Chen, Lawrence Lee
Oct 22, 2008·International Ophthalmology Clinics·Teresa C ChenJohannes F de Boer
Dec 1, 2009·Journal français d'ophtalmologie·F MatontiJ Conrath
Jan 15, 2010·Investigative Ophthalmology & Visual Science·Ramiro S MaldonadoCynthia A Toth
Jan 29, 2011·Retina·Susanne BinderCarl Glittenberg
Feb 2, 2011·Investigative Ophthalmology & Visual Science·Justis P EhlersCynthia A Toth
Oct 22, 2013·Survey of Ophthalmology·Reetika SharmaTanuj Dada
Mar 13, 2014·Current Opinion in Ophthalmology·Justis P EhlersSunil K Srivastava
May 2, 2014·The British Journal of Ophthalmology·Justis P EhlersSunil K Srivastava

❮ Previous
Next ❯

Citations

Apr 30, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·B V StanzelF G Holz
Jul 21, 2016·Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft·S SiebelmannP Steven
Apr 27, 2019·Eye·Rino Frisina, Alessandro Meduri
Jan 15, 2016·Journal of Glaucoma·Sebastian SiebelmannThomas Dietlein
Jan 13, 2018·Ergonomics·Andreas Gregoriades, Alistair Sutcliffe
Jul 28, 2020·Survey of Ophthalmology·Jeewan S TitiyalNamrata Sharma

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.