A pilot trial of BIS monitoring for procedural sedation in the emergency department

Emergency Medicine Australasia : EMA
Daniel M FatovichMichael J Paech

Abstract

Procedural sedation is common in the ED. However, there is no objective physiologic parameter available to monitor a patient's conscious state. The Bispectral Index (BIS) monitor has been validated as an objective measure of depth of anaesthesia. We studied the BIS monitor for this role in procedural sedation. A prospective, observational study with convenience sampling of adult patients in ED who underwent procedural sedation. Patients were treated according to standard practice and sedated as determined by the treating physician. Treating physicians were blinded to the BIS value. BIS values were recorded and compared to the Observer's Assessment of Alertness/Sedation Scale (OAAS). Upon recovery, patients were asked about recall of events while they were sedated. Twelve patients were enrolled and 110 paired readings from 11 patients (7 male) were obtained. It was not possible to obtain readings from one patient. The mean age was 58 years (range 20-94). The Spearman correlation between BIS and OAAS was 0.027 (95% CI -0.582-0.617). For the three patients who received propofol, the correlation was 1.0. There were no episodes of explicit recall of events during the period of sedation. BIS monitoring is feasible in the ED. Our smal...Continue Reading

References

Mar 1, 1996·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·E R SwansonS Mathias
Mar 19, 1999·Journal of Clinical Neurophysiology : Official Publication of the American Electroencephalographic Society·K G Jordan
Sep 2, 2000·Anesthesiology·J E PollockN Polissar
Jan 11, 2000·Emergency Medicine Clinics of North America·P Blackburn, R Vissers
Mar 29, 2001·Anesthesia and Analgesia·G MychaskiwB J Heath
Jun 9, 2001·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·N A SandlerM Sabino
Jul 27, 2001·Acta Anaesthesiologica Scandinavica·G BarrJ G Jakobsson
Jan 10, 2002·Anesthesiology Clinics of North America·C Rosow, P J Manberg
Jun 5, 2003·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·James R MinerDavid Plummer

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Citations

Apr 25, 2007·Emergency Medicine Journal : EMJ·Alex SwannDaniel M Fatovich
Aug 10, 2011·Emergency Medicine Australasia : EMA·Anthony BellJohn Pasco
Oct 2, 2012·Pediatric Emergency Care·Carmen GambleSamina Ali

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