A plant locus essential for phylloquinone (vitamin K1) biosynthesis originated from a fusion of four eubacterial genes.

The Journal of Biological Chemistry
Jeferson GrossJörg Meurer

Abstract

Phylloquinone is a compound present in all photosynthetic plants serving as cofactor for Photosystem I-mediated electron transport. Newly identified seedling-lethal Arabidopsis thaliana mutants impaired in the biosynthesis of phylloquinone possess reduced Photosystem I activity. The affected gene, called PHYLLO, consists of a fusion of four previously individual eubacterial genes, menF, menD, menC, and menH, required for the biosynthesis of phylloquinone in photosynthetic cyanobacteria and the respiratory menaquinone in eubacteria. The fact that homologous men genes reside as polycistronic units in eubacterial chromosomes and in plastomes of red algae strongly suggests that PHYLLO derived from a plastid operon during endosymbiosis. The principle architecture of the fused PHYLLO locus is conserved in the nuclear genomes of plants, green algae, and the diatom alga Thalassiosira pseudonana. The latter arose from secondary endosymbiosis of a red algae and a eukaryotic host indicating selective driving forces for maintenance and/or independent generation of the composite gene cluster within the nuclear genomes. Besides, individual menF genes, encoding active isochorismate synthases (ICS), have been established followed by splitting ...Continue Reading

References

Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Oct 27, 1998·Trends in Biochemical Sciences·T DandekarP Bork
Feb 17, 2000·Biochimica Et Biophysica Acta·A BridgeD J Morré
Apr 26, 2001·Apoptosis : an International Journal on Programmed Cell Death·S P SaxenaL G Israels
Jul 5, 2001·Proceedings of the National Academy of Sciences of the United States of America·I YanaiC DeLisi
Mar 23, 2002·Science·Motoaki SekiKazuo Shinozaki
Sep 10, 2002·Proceedings of the National Academy of Sciences of the United States of America·William MartinDavid Penny
Jan 14, 2003·Annual Review of Biophysics and Biomolecular Structure·John H Golbeck
Dec 12, 2003·Nature·Adam Ben-ShemNathan Nelson
Dec 30, 2003·BioFactors·K LochnerM Böttger
May 18, 2004·The Plant Journal : for Cell and Molecular Biology·Lina Lezhneva, Jörg Meurer
Feb 24, 2005·Annual Review of Plant Biology·Brenda S J Winkel
Apr 16, 2005·Current Opinion in Biotechnology·Pascal J LopezChris Bowler
Jun 1, 2005·Plant Physiology·Peter BrodersenJohn Mundy

❮ Previous
Next ❯

Citations

Nov 23, 2011·Biochemistry·Michael D McConnellKevin E Redding
Mar 27, 2009·Proceedings of the National Academy of Sciences of the United States of America·Joshua R WidhalmGilles J C Basset
Dec 10, 2009·Proceedings of the National Academy of Sciences of the United States of America·Yinan YuanChung-Jui Tsai
Aug 17, 2011·Proceedings of the National Academy of Sciences of the United States of America·Lucia Eugeni PillerMichel Havaux
Mar 1, 2012·Journal of Experimental Botany·Lucia Eugeni PillerCéline Besagni
May 3, 2008·Plant Physiology·Christophe GarcionJean-Pierre Métraux
Mar 1, 2012·The Plant Cell·Teresa B FitzpatrickAlisdair R Fernie
Apr 25, 2008·BMC Evolutionary Biology·Jeferson GrossDebashish Bhattacharya
Apr 11, 2012·Food & Nutrition Research·Sarah L Booth
Sep 19, 2008·Phytochemistry·Chloë van OostendeGilles J C Basset
Mar 30, 2011·The Plant Journal : for Cell and Molecular Biology·Hoi Yee ChuAnne Osbourn
Jul 16, 2010·The Plant Journal : for Cell and Molecular Biology·Fabienne FurtGilles J C Basset
May 7, 2010·The Plant Journal : for Cell and Molecular Biology·Maria C Suarez RodriguezJohn Mundy
Jan 15, 2015·Biochimica Et Biophysica Acta·Huixia YangCongming Lu
Jul 6, 2010·Biochimica Et Biophysica Acta·Beatrycze Nowicka, Jerzy Kruk
Jan 13, 2015·Molecular Plant·Joshua R Widhalm, Natalia Dudareva
Feb 20, 2018·Bioscience, Biotechnology, and Biochemistry·Makoto Kawamukai
Jun 25, 2017·Annual Review of Phytopathology·Matthias L BerensKenichi Tsuda
Sep 29, 2019·Plant Signaling & Behavior·Yuan QinHans Thordal-Christensen
Mar 7, 2007·The Journal of Biological Chemistry·Linnka Lefebvre-LegendreJean-David Rochaix
Mar 1, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Patrick OrlandoLuca Tiano
Sep 6, 2018·Annual Review of Genetics·Hans-Wilhelm NützmannAnne Osbourn

❮ Previous
Next ❯

Related Concepts

Related Feeds

ASBMB Publications

The American Society for Biochemistry and Molecular Biology (ASBMB) includes the Journal of Biological Chemistry, Molecular & Cellular Proteomics, and the Journal of Lipid Research. Discover the latest research from ASBMB here.