A Population-Based Assessment of 24-Hour Ocular Perfusion Pressure Among Patients With Primary Open Angle Glaucoma: The Handan Eye Study

Asia-Pacific Journal of Ophthalmology
Yuan Bo LiangNing Li Wang

Abstract

To compare the 24-hour ocular perfusion pressure (OPP) among patients with primary open angle glaucoma (POAG) and those with suspected POAG identified in a population-based study in China. Forty-seven patients with POAG and 35 with suspected POAG attended the 24-hour OPP study. Intraocular pressure (IOP) and blood pressure (BP) were measured at 2, 6, and 10 AM and 2, 6, and 10 PM. Subjects were not taking any medications to lower IOP, which was measured with Goldmann applanation in an upright sitting position. Blood pressure was measured in a supine position using a digital automatic BP monitor (OMRON, model HEM-907). Mean arterial pressure was calculated as diastolic BP + 1[Fraction Slash]3 × (systolic BP - diastolic BP). Mean OPP (MOPP) was defined as 2[Fraction Slash]3 × mean arterial pressure - IOP, systolic OPP (SOPP) was defined as 2[Fraction Slash]3 × systolic BP - IOP, and diastolic OPP (DOPP) was defined as 2[Fraction Slash]3 × diastolic BP - IOP. After adjustment for age, sex, and IOP, the maximum, mean, and minimum SOPP, DOPP, and MOPP were statistically significantly lower in subjects with POAG than in those with suspected POAG (P < 0.05). The minimum MOPP, SOPP, and DOPP occurred from 10 AM to 2 PM in approximately...Continue Reading

References

Aug 13, 1988·Lancet·E O'BrienK O'Malley
Jul 1, 1995·Archives of Ophthalmology·M C LeskeA P Schachat
Jun 1, 1994·Archives of Ophthalmology·M C LeskeL Hyman
Jun 1, 2001·American Journal of Ophthalmology·S DranceUNKNOWN Collaborative Normal-Tension Glaucoma Study Group
Jul 27, 2001·Progress in Retinal and Eye Research·S S Hayreh
Aug 2, 2002·Progress in Retinal and Eye Research·Josef FlammerEinar Stefánsson
Jan 14, 2003·Archives of Ophthalmology·M Cristina LeskeUNKNOWN Early Manifest Glaucoma Trial Group
Jul 1, 2004·Journal of Glaucoma·Paul MitchellJie Jin Wang
Aug 2, 2005·Ophthalmology Clinics of North America·Alon HarrisHana J Garzozi
Feb 24, 2006·American Journal of Ophthalmology·Tien Yin WongSteven Shea
Jan 2, 2007·Investigative Ophthalmology & Visual Science·Jaewan ChoiMichael S Kook
Feb 17, 2007·Blood Pressure Monitoring·Maria C S Lenz, Denis Martinez
Mar 27, 2007·Sleep Medicine·Michael H SmolenskyFrancesco Portaluppi
Jul 14, 2007·Ophthalmology·M Cristina LeskeUNKNOWN EMGT Group
Jul 17, 2007·Ophthalmology·M Cristina LeskeUNKNOWN BESs Study Group
Apr 29, 2008·Investigative Ophthalmology & Visual Science·Sunny Y ShenTin Aung
Apr 2, 2009·Korean Journal of Ophthalmology : KJO·Soo Geun JoeMichael S Kook
Apr 9, 2009·Ophthalmic Epidemiology·Yuan Bo LiangUNKNOWN Handan Eye Study Group
May 29, 2009·Investigative Ophthalmology & Visual Science·Kyung Rim SungMichael S Kook
Feb 19, 2010·Investigative Ophthalmology & Visual Science·Yingfeng ZhengTin Aung
Sep 8, 2011·Investigative Ophthalmology & Visual Science·Yuan Bo LiangUNKNOWN Handan Eye Study Group
Sep 13, 2011·Investigative Ophthalmology & Visual Science·Yuanbo LiangUNKNOWN Handan Eye Study Group

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Citations

Oct 24, 2019·Journal of Ophthalmology·Chun Hing Ho, Jasper K W Wong
Mar 30, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Alice C Verticchio VercellinFrancesco Oddone
Jan 29, 2020·Progress in Retinal and Eye Research·Alon HarrisJulia Arciero

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