A population-based birth cohort study of the association between childhood-onset asthma and exposure to industrial air pollutant emissions

Environment International
Stéphane ButeauAudrey Smargiassi

Abstract

Studies of the association between air pollution and asthma onset have mostly focused on urban and traffic-related air pollution. We investigated the associations between exposure to industrial emissions and childhood-onset asthma in a population-based birth cohort in Quebec, Canada, 2002-2011. The cohort was built from administrative health databases. We developed separately for PM2.5 and SO2 different metrics representing children's time-varying residential exposure to industrial emissions: 1) yearly number of tons of air pollutant emitted by industries located within 2.5 km of the residence; 2) distance to the nearest "major emitter" (≥100 tons) of either PM2.5 and SO2 within 7.5 km of the residence, and; 3) tons of air pollutant emitted by the nearest "major emitter" within 7.5 km, weighted by the inverse of the distance and the percentage of time that the residence was downwind. To handle the large number of zeros (i.e., children unexposed) we decomposed the exposure variable into two covariates simultaneously included in the regression model: a binary indicator of exposure and a continuous exposure variable centered at the mean value among exposed children. We performed Cox models using age as the time axis, adjusted for ...Continue Reading

Citations

Jun 27, 2020·International Journal of Environmental Research and Public Health·Annunziata Faustini, Marina Davoli
Aug 6, 2020·International Journal of Environmental Research and Public Health·Yukiko Nishihama On Behalf Of The Japan Environment And Children's Study Group
Oct 27, 2020·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Deborah A GentileDavid P Skoner
Feb 2, 2021·Wilderness & Environmental Medicine·Yaozu ZhangJie Wang
Jul 14, 2020·The Science of the Total Environment·Yongna YuanChunyan Zhao
Mar 7, 2021·Children·Emanuela di PalmoAndrea Pession
May 1, 2021·International Journal of Environmental Research and Public Health·Rachel D FreidCarlos A Camargo

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