A population-based, complete follow-up of 146 consecutive patients after transanal mucosectomy for Hirschsprung disease

Journal of Pediatric Surgery
Malla I NeuvonenMikko P Pakarinen

Abstract

The objective of the study is to define the population-based bowel functional outcomes and enterocolitis following transanal endorectal pull-through (TEPT) in patients with Hirschsprung disease (HD) treated at our institution between 1986 and 2011. 146 consecutive patients who had undergone primary surgical treatment for HD were included. The median follow-up time was 15 (3-33) years. The clinical details and prevalence of enterocolitis were evaluated in all patients, and bowel function in patients >3years of age with functional intestino-anal continuity. No patients were lost to follow-up. Overall survival was 98%. The level of disease was rectosigmoid in 83%, long segment in 7%, total colonic in 4%, and extending up to the small bowel in 6%. 29% had an associated syndrome. 22% had a preoperative stoma. Operations included TEPT (89%), proctocolectomy with ileoanal anastomosis in 9%, and 3% had a permanent endostomy owing to small intestinal aganglionosis. One patient underwent intestinal transplantation. At the latest follow-up, 42% had occasional soiling, 12% had frequent soiling and 46% had no soiling. Constipation occurred in 9%. An associated syndrome was the only predictor for soiling or constipation (OR 4.3, 95% CI 1.5-1...Continue Reading

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Citations

Mar 10, 2016·Journal of Pediatric Surgery·David CoylePrem Puri
Jul 17, 2015·Pediatric Surgery International·Danielle Mc Laughlin, Prem Puri
Jul 8, 2016·Pediatric Surgery International·J ZimmerP Puri
Sep 24, 2016·Pediatric Surgery International·Christian TomuschatPrem Puri
Nov 18, 2016·Pediatric Surgery International·Christian TomuschatPrem Puri
Mar 21, 2017·Current Opinion in Pediatrics·Maggie L Westfal, Allan M Goldstein
Jan 18, 2017·Journal of Pediatric Surgery·Kristin BjørnlandUNKNOWN Nordic Pediatric Surgery Study Consortium
Oct 29, 2018·International Journal of Colorectal Disease·Tianqi ZhuJiexiong Feng
Sep 3, 2020·European Journal of Pediatric Surgery : Official Journal of Austrian Association of Pediatric Surgery ... [et Al] = Zeitschrift Für Kinderchirurgie·Cornelia ByströmAnna Löf Granström
Jan 7, 2017·Pediatric Surgery International·Tomoaki TaguchiSatoshi Ieiri
Jun 27, 2020·Orphanet Journal of Rare Diseases·Kristiina KyrklundMikko P Pakarinen
Jan 19, 2017·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·Girolamo MattioliAlessio Pini Prato
Nov 4, 2020·Archives of Disease in Childhood·Benjamin Saul Raywood AllinUNKNOWN NETS2HD collaboration
Mar 13, 2021·Journal of Pediatric Surgery·Joseph R DavidsonJoe Curry
Dec 7, 2020·Journal of Pediatric Surgery·Pedro Luiz Toledo de Arruda LourençãoMaria Aparecida Marchesan Rodrigues
Jul 3, 2021·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·Hannah M E Evans-BarnsSebastian K King

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