A population-based study of congenital diaphragmatic hernia

Teratology
C P TorfsL H Honoré

Abstract

From 1983 through 1987, in a California population of 718,208 births, 237 infants were born with a congenital diaphragmatic hernia (CDH), a birth prevalence of 3.30 per 10,000 total births (live births and stillbirths). We proposed that the various types of this defect, characterized by their different pathogeneses, would be reflected in differences in their descriptive epidemiologies. We evaluated various demographic, maternal, and infant characteristics for three major types of defects, the Morgagni hernia, the pars sternalis hernia, and the posterolateral hernia, categorizing the latter type into isolated defect (N = 129), multiple congenital anomalies including nonchromosomal syndromes (N = 86), trisomies (N = 10), and chromosomal anomalies other than trisomies (N = 2). For the posterolateral hernia, we present the distribution of associated anomalies (43%) and specifically of midline defects (19%). Although the number of cases for the Morgagni hernia (N = 5) and the pars sternalis hernia (N = 5) were small, comparisons with the posterolateral hernia suggested lower sex ratios, of borderline significance for the pars sternalis hernia (P < 0.09), and higher mean maternal ages for both groups. Within the posterolateral type, ...Continue Reading

References

Mar 1, 1997·Prenatal Diagnosis·P A Mowery-RushtonW A Hogge
Oct 17, 1998·Pediatric Pulmonology·H IJsselstijn, Dick Tibboel
May 17, 2003·Birth Defects Research. Part A, Clinical and Molecular Teratology·D Kim WallerAllen A Mitchell
Dec 17, 2004·Birth Defects Research. Part A, Clinical and Molecular Teratology·Marieke van DoorenClaudine Torfs
Jun 20, 2007·Pediatric Surgery International·G CasacciaP Bagolan
Apr 11, 2008·Pediatric Surgery International·Sandra MontedonicoPrem Puri
Oct 15, 2013·Hernia : the Journal of Hernias and Abdominal Wall Surgery·T S SchiergensA Kleespies
Jun 1, 1996·Obstetrics and Gynecology·C CannonD J Dudley
Dec 16, 1997·Obstetrics and Gynecology·N J SebireK H Nicolaides
Sep 15, 2000·European Journal of Obstetrics, Gynecology, and Reproductive Biology·Richard KeijzerDick Tibboel
Feb 26, 2004·Paediatric Respiratory Reviews·M Hösgor, Dick Tibboel
Apr 20, 2001·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·M S SongL K Hornberger
Apr 16, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E GarneEuroscan Study Group
Apr 16, 2002·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·B Thilaganathan
Jul 20, 2011·Journal of Laparoendoscopic & Advanced Surgical Techniques. Part a·James Mitchell Stewart AndrewsGordon Alexander MacKinlay
May 11, 2002·Clinical Dysmorphology·Alice S BrooksDick Tibboel
Oct 3, 2002·American Journal of Respiratory and Critical Care Medicine·Desmond Bohn
May 19, 2009·American Journal of Respiratory Cell and Molecular Biology·Robin D ClugstonJohn J Greer
Jan 5, 2012·Orphanet Journal of Rare Diseases·Juan A Tovar
Dec 15, 2010·Journal of Medical Case Reports·Pier Paolo BassareoRoberto Tumbarello
May 15, 2013·Journal of Medical Case Reports·Enrica BianchiMarco Artico
Jan 19, 2012·Nutrients·Margaret Clagett-Dame, Danielle Knutson
Aug 24, 2011·World Journal of Gastrointestinal Endoscopy·Francesco LassandroRoberto Muto
Sep 11, 2013·JSLS : Journal of the Society of Laparoendoscopic Surgeons·Joseph KimCelia Divino
Oct 28, 2005·Proceedings of the National Academy of Sciences of the United States of America·Li-Ru YouMing-Jer Tsai
Apr 19, 2003·Proceedings of the National Academy of Sciences of the United States of America·Wenlin YuanDavid M Ornitz
Aug 8, 2007·Archives of Gynecology and Obstetrics·Cornelia BeckConstantin S von Kaisenberg
Jul 6, 2014·Seminars in Pediatric Surgery·Dario O Fauza
Jun 12, 2014·Journal of Pediatric Gastroenterology and Nutrition·Anne PierogAli Mencin
Sep 10, 2014·Obstetrics and Gynecology·K D Wenstrom, Stephen R Carr
Dec 3, 2014·Seminars in Fetal & Neonatal Medicine·Julia WynnWendy K Chung
Nov 28, 2009·Nutrition Reviews·Leonardus W J E BeurskensRégine P M Steegers-Theunissen
May 1, 2010·African Journal of Paediatric Surgery : AJPS·Tutku OzdoganMavisen Iscen
Aug 15, 1993·American Journal of Medical Genetics·L H HonoréC J Curry
Jan 21, 2014·Journal of Pediatric Surgery·Jarod P McAteerAdam B Goldin
Oct 1, 1993·American Journal of Obstetrics and Gynecology·A E DonnenfeldS Weiner
Aug 21, 2012·Journal of Pediatric Surgery·Ibrahim Akkoyun, Melahat Keçecioğlu
Nov 8, 2011·Journal of the American College of Surgeons·Burkhard H A von RahdenUlrich A Dietz
Jun 29, 2011·Seminars in Pediatric Surgery·Steffi MayerDietrich Kluth
Jul 26, 2011·European Journal of Medical Genetics·Florence PetitSylvie Manouvrier-Hanu

Citations

Oct 1, 1979·Archives of Surgery·H G MishalanyM M Woolley
Jun 1, 1978·Journal of Pediatric Surgery·M R HarrisonO Knutrud
Aug 1, 1976·Journal of Medical Genetics·T J David, C A Illingworth
Oct 1, 1991·American Journal of Obstetrics and Gynecology·K D WenstromJ W Hanson
Nov 1, 1990·The New England Journal of Medicine
Feb 1, 1990·The Journal of Pediatrics·C CunniffM C Jones
Jul 1, 1990·Journal of Pediatric Surgery·L W MilneM R Harrison
Sep 1, 1990·The Journal of Pediatrics·R F BoedyW P Kanto
Sep 1, 1989·Journal of Pediatric Surgery·D C HitchO M Rennert
Oct 1, 1988·Journal of Pediatric Surgery·D R BenjaminJ R Siebert
Dec 1, 1986·Environmental Health Perspectives·J M Manson
May 1, 1985·American Journal of Medical Genetics·A Czeizel, M Kovács
Aug 1, 1985·Journal of Pediatric Surgery·N S AdzickA A deLorimier
Mar 31, 1962·Lancet·N BUTLER, A E CLAIREAUX
Mar 31, 1962·Lancet·R E CARTERE ABERDEEN

Related Concepts

Autosomal Chromosome Disorders
Pathogenesis
Seasonal Variation
Thyroid Hormone Plasma Membrane Transport Defect
Hernia
Gardner Morrisson Abbot Syndrome
Diaphragmatic Hernia
Multiple Congenital Anomalies
Autosome Abnormalities
Birth

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