A population-based study of depressed mood in middle-aged, Australian-born women

Menopause : the Journal of the North American Menopause Society
L DennersteinVictor W Henderson

Abstract

There has been controversy about the relationship between menopause and depression. This study utilizes a unique prospective population-based data set of middle-aged, Australian-born women to identify determinants of depressed mood. The Melbourne Women's Midlife Health Project sample consisted of 438 women aged 45 to 55 at baseline; they were followed annually for 11 years. Of this group, 314 (72%) completed the Center for Epidemiologic Studies Depression Scale (CES-D) scale in year 11 to measure depressed mood. Variables measured at baseline and annually included negative mood (measured with Affectometer) and psychosocial, hormonal, health, and lifestyle factors. Women who had the highest CES-D scores were those who by year 11 were still in the menopause transition stage (had not reached final menstrual period) or had experienced surgical menopause. CES-D correlated with negative mood measured concurrently (r = 0.63) and baseline negative mood (r = 0.37). There was a significant reduction in negative mood for all menopause status groups, but those who experienced surgical menopause showed less reduction than other women. Ever-use or number of years of use of hormone therapy made no difference to CES-D outcome. CES-D was associ...Continue Reading

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Citations

Aug 2, 2005·Lancet·Martha HickeyDavid W Sturdee
Oct 24, 2013·Menopause : the Journal of the North American Menopause Society·Florence PerquierFrançoise Clavel-Chapelon
Feb 10, 2007·Menopause : the Journal of the North American Menopause Society·Lorraine DennersteinJeanne Leventhal Alexander
Jan 8, 2008·Menopause : the Journal of the North American Menopause Society·Nancy Fugate WoodsSullivan Mitchell
Jan 27, 2009·Menopause : the Journal of the North American Menopause Society·Joanne RyanLorraine Dennerstein
Apr 20, 2010·Menopause : the Journal of the North American Menopause Society·Sermin Timur, Nevin Hotun Sahin
Jun 10, 2010·Menopause : the Journal of the North American Menopause Society·Ellen W Freeman
Mar 5, 2011·Menopause : the Journal of the North American Menopause Society·James Francis CarmodyNicholas Olendzki
Sep 9, 2011·Menopause : the Journal of the North American Menopause Society·Carolyn J GibsonKaren A Matthews
Oct 27, 2011·Menopause : the Journal of the North American Menopause Society·Wendy K MarshAnthony J Rothschild
Mar 15, 2012·Menopause : the Journal of the North American Menopause Society·Vanessa de Souza Santos MachadoAarão Mendes Pinto-Neto
Jul 5, 2012·Menopause : the Journal of the North American Menopause Society·Tzvia BlumsteinLiat Lerner-Geva
Sep 21, 2013·Menopause : the Journal of the North American Menopause Society·Katherine M NewtonAndrea Z LaCroix
Jun 24, 2014·Women's Health·Christina BryantFiona Judd
Apr 10, 2014·Menopause : the Journal of the North American Menopause Society·Katherine F BurnCassandra Szoeke
Jun 13, 2006·Climacteric : the Journal of the International Menopause Society·N Fugate WoodsE Sullivan Mitchell
Dec 3, 2011·Climacteric : the Journal of the International Menopause Society·M HickeyF Judd
Apr 25, 2007·Climacteric : the Journal of the International Menopause Society·J R GuthrieL Dennerstein
Dec 1, 2007·Climacteric : the Journal of the International Menopause Society·K K VescoH D Nelson
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