A Population-Based Study of the Epidemiology of Chronic Hypoparathyroidism

Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research
Thenmalar VadivelooGraham P Leese

Abstract

There are very few reports on the epidemiology of chronic hypoparathyroidism. A population-based study was undertaken to describe the prevalence and incidence of hypoparathyroidism in Tayside, Scotland. Data on biochemistry, hospital admissions, prescribing, and death records in Tayside, Scotland, from 1988 to 2015 were linked electronically. Patients with at least three serum albumin-corrected calcium concentrations below the reference range that were taken in an outpatient setting were included in the study. Patients with severe chronic kidney disease before low calcium were excluded from the study. Patients with hypocalcemia were included if they had either previous neck surgery/irradiation, a low serum parathyroid hormone (PTH), or were treated with vitamin D. Patients were identified as having either a postsurgical or a nonsurgical cause or had secondary hypoparathyroidism, eg, hypomagnesemia. Overall, 18,955 patients were identified with hypocalcemia. Of these, 222 patients had primary hypoparathyroidism, 116 with postsurgical and 106 with nonsurgical chronic hypoparathyroidism. In 2015, the prevalence of primary hypoparathyroidism was 40 per 100,000, with a rate of 23 and 17 per 100,000, respectively, for postsurgical an...Continue Reading

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Citations

Oct 31, 2018·Clinical Endocrinology·Thenmalar VadivelooGraham P Leese
May 21, 2019·Current Opinion in Rheumatology·Natalie E Cusano, John P Bilezikian
Aug 2, 2020·The Journal of Clinical Endocrinology and Metabolism·Kristina S ChenJohn P Bilezikian
Dec 13, 2019·MMW Fortschritte der Medizin·Stephan PetersennHeide Siggelkow
Aug 28, 2020·Cancer Management and Research·Daoqi ShenXialian Xu
Oct 19, 2019·World Journal of Clinical Cases·Li-Na DingWen-Bin Shang
Jun 20, 2020·Archives of Endocrinology and Metabolism·Julián Zea LoperaAlejandro Román-González
Sep 9, 2021·Calcified Tissue International·Ceyla Konca DegertekinMustafa Eroglu

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