A population-based study of the usefulness of screening for neuroblastoma

Lancet
W G WoodsB Lemieux

Abstract

Neuroblastoma has many characteristics which suggest that preclinical detection might improve outcome. The Quebec Neuroblastoma Screening Project was initiated to determine whether mass screening could reduce mortality in a large cohort of infants. As an early endpoint, we report whether screening could reduce the incidence of poor-prognosis neuroblastoma in children with advanced-stage disease over 1 year of age. All 476,603 children born in the province of Quebec during the 5-year period of May 1, 1989, to April 30, 1994, were eligible for urinary assay of homovanillic acid and vanillylmandelic acid at 3 weeks and 6 months of age. Children with a positive screen were referred to one of four paediatric cancer centres in the province for uniform evaluation and treatment if necessary. Standardised incidence ratios (SIRs) were calculated for neuroblastoma in the province and two similar population-based controls, the state of Minnesota and the province of Ontario, during the same period of time and with similar ascertainment procedures. Compliance with screening in Quebec province was 91% at 3 weeks (n = 425,816) and 74% at 6 months (n = 349,706). Through July 31, 1995, with a follow-up of the birth cohort of 15-75 months, 118 ca...Continue Reading

References

May 1, 1992·The American Journal of Pediatric Hematology/oncology·G M Brodeur, A Nakagawara
Oct 21, 1992·International Journal of Cancer. Journal International Du Cancer·C A Stiller, D M Parkin
Dec 16, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R ErttmannT Philip
Apr 1, 1955·Pediatrics·E M UHLMANN, C VON ESSEN

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Citations

Aug 26, 2000·Genes, Chromosomes & Cancer·Y Kaneko, A G Knudson
May 19, 2005·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Victoria CastelUNKNOWN Grupo Español de Neuroblastoma (SEOP)
Apr 25, 2000·Indian Journal of Pediatrics·S Shah, Y Ravindranath
Jun 23, 2006·Analytical and Bioanalytical Chemistry·Tomomi HasegawaTsutomu Masujima
Oct 21, 2009·Current Oncology Reports·Sabine Mueller, Katherine K Matthay
Jul 6, 2004·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·M B MichalowskiUNKNOWN Groupe Neuroblastome de la Société Française d'Oncologie Pédiatrique
Dec 31, 2003·Gene·Max M van Noesel, Rogier Versteeg
Apr 3, 2001·Clinica Chimica Acta; International Journal of Clinical Chemistry·M J MageraP Rinaldo
Dec 24, 1997·The Journal of Pediatrics·J BlattJ L Ross
Aug 1, 1997·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R P Castleberry
Mar 28, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·W G WoodsG M Brodeur
Dec 16, 1998·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R ErttmannT Philip
May 7, 2004·The New England Journal of Medicine·Yoshitaka Tsubono, Shigeru Hisamichi
Apr 5, 2002·The New England Journal of Medicine·Freimut H SchillingJoerg Michaelis
Apr 5, 2002·The New England Journal of Medicine·William G WoodsBernard Lemieux
Jul 16, 1997·Journal of the National Cancer Institute·F H Schilling
Jun 24, 1999·Journal of the National Cancer Institute·M S LinetS S Devesa
Jul 19, 2001·Journal of the National Cancer Institute·M S PepeY Yasui
Aug 4, 2005·Journal of the National Cancer Institute·Lee SoderstromBernard Lemieux
Oct 27, 1998·Journal of Pediatric Hematology/oncology·T TagaS Ohta
Oct 19, 2000·Journal of Pediatric Hematology/oncology·K K Matthay, D Stram
Jan 25, 2003·Journal of Pediatric Hematology/oncology·William G Woods
Jan 25, 2003·Journal of Pediatric Hematology/oncology·Gabriele DobrovoljskiHerwig Lackner
Dec 20, 2012·Journal of Pediatric Hematology/oncology·Stefano GiulianiTracy Grikscheit
Jun 20, 2013·The Journal of Clinical Investigation·Yuyan ZhuAkira Nakagawara
Dec 2, 2014·Pediatric Clinics of North America·Meredith S Irwin, Julie R Park
Oct 22, 2014·Nature Reviews. Clinical Oncology·Garrett M Brodeur, Rochelle Bagatell
Nov 9, 2012·World Journal of Surgery·Denis Andrew CozziCarlo Dominici
Jan 22, 2013·Journal of Pediatric Surgery·Robert C Shamberger
Aug 17, 2010·Seminars in Oncology·Jennifer M CroswellBarnett S Kramer
May 11, 2010·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Fergal C Kelleher, Ray McDermott
Feb 23, 2010·Current Problems in Cancer·Natia EsiashviliHoward M Katzenstein
Jan 29, 2008·Seminars in Oncology Nursing·Judith J Smith, Christine D Berg
Apr 24, 2007·European Journal of Internal Medicine·Michael J Duffy
Mar 28, 2009·Pediatric Blood & Cancer·Logan G Spector, Amy M Linabery
Aug 4, 2005·Pediatric Blood & Cancer·William G Woods

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