A porcine model for renal hemodynamic study during laparoscopy

The Journal of Surgical Research
A W ChiuR K Babayan

Abstract

Laser Doppler flowmetry (LDF) is a sensitive method for the measurement of microvascular blood flow in tissue. The method has been found useful for estimating skin, liver, or gastrointestinal blood flow. Whether it can be applied laparoscopically and whether it is able to measure the intraparenchymal blood flow of an intraabdominal organ is still unknown. In a pilot study, 6 pigs received a laparotomy for placement of a 19-gauge LDF needle probe into the renal parenchyma. Three different locations of the lower pole kidney were chosen for the blood flow measurement. The reliability of using the instrument to measure the renal tissue blood flow was assessed by comparison of the results of renal arterial blood flow obtained from a well-established methodology--ultrasonic Doppler flowmetry. Recordings were taken following (a) intravenous administration of 0.005 mg/kg norepinephrine, (b) manual compression of the suprarenal aorta, and (c) intravenous injection of a lethal dose of phenobarbital (50 mg/kg). Measurements of LDF were possible in all kidney units. The renal tissue perfusion detected by LDF correlated excellently with the renal arterial blood flow under different renal perfusion pressures. The feasibility of using LDF pro...Continue Reading

Citations

Apr 23, 2013·Surgical Endoscopy·Chris Westgarth-TaylorJonathan Karpelowsky
Apr 22, 2011·Urology·Joshua D WiesenthalKenneth T Pace
Sep 16, 2008·The Surgical Clinics of North America·Simon Bergman, W Scott Melvin
Dec 30, 2014·Minimally Invasive Therapy & Allied Technologies : MITAT : Official Journal of the Society for Minimally Invasive Therapy·Masanari ShimadaGo Watanabe
Dec 20, 2005·Surgical Endoscopy·S V DemyttenaereG M Fried
Dec 13, 2006·Surgical Endoscopy·Scbastian DemyttenaereGerald M Fried
Jan 15, 2003·European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society for Vascular Surgery·P AlricP Colson

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