A positive wave at 8 ms (P8) and modified auditory brainstem responses measurement in auditory neuropathy spectrum disorder

International Journal of Pediatric Otorhinolaryngology
Claus-Michael SchmidtArne Knief

Abstract

Auditory neuropathy spectrum disorder (ANSD) is characterized by absent or atypical auditory brainstem responses (ABR), recordable otoacoustic emissions and/or cochlear microphonics. Modification of ABR stimuli is discussed to improve wave V synchronization in ANSD patients. Ten ANSD children (seven unilateral) underwent ABR measurement with an alternating stimulus (40.5s(-1)), constant rarefaction and condensation stimuli, a reduced click-rate (11.1s(-1)) and a chirp-stimulus. The results showed no remarkably better synchronization with modified stimuli. Whereas higher levels showed no synchronization, reproducible positive waves at 8 ms (P8) at intensities of 65-85 dB were found in six patients with all stimuli. We suggest an ipsilateral auditory origin of the positive potentials at 8 ms. They could be characteristic of synchronization abnormalities in some cases of ANSD.

References

Aug 1, 1978·British Journal of Clinical Pharmacology·D G Gibson
Jan 1, 1969·Acta Oto-laryngologica. Supplementum·N Yoshie, T Okudaira
Apr 1, 1981·The Laryngoscope·O Ozdamar, L Stein
Mar 21, 1998·Ear and Hearing·C I BerlinL J Hood
Nov 27, 1999·Hearing Research·G A O'Beirne, R B Patuzzi
Mar 30, 2000·The Journal of the Acoustical Society of America·T DauB Kollmeier
Nov 20, 2002·Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology·Dong X NongYutaka Noda
May 25, 2005·Neurology·Miriam S Welgampola, James G Colebatch
Dec 29, 2005·International Journal of Audiology·Suzanne C PurdyGreg A O'Beirne
Apr 1, 2006·International Journal of Pediatric Otorhinolaryngology·Astrid FoerstMartin Walger
May 27, 2008·International Journal of Pediatric Otorhinolaryngology·Petros V VlastarakosStavros Korres
Dec 17, 2008·Clinical Neurophysiology : Official Journal of the International Federation of Clinical Neurophysiology·Miriam S WelgampolaJohn P Carey
Jul 24, 2010·The Journal of the Acoustical Society of America·Claus ElberlingManuel Don
Jul 24, 2010·The Journal of the Acoustical Society of America·Matthew A PetoeWayne J Wilson
Sep 3, 2010·Journal of the American Academy of Audiology·Mario Cebulla, Claus Elberling

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Citations

Jan 2, 2014·International Journal of Pediatric Otorhinolaryngology·Thomas P Nikolopoulos
Dec 10, 2015·American Journal of Audiology·Gabriel Anne Bargen

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