A potent new beta2-adrenoceptor blocking agent

British Journal of Pharmacology
J L ImbsC G Wermuth


1 (t-Butyl-amino-3-ol-2-propyl) oximino-9 fluorene is a new beta2-adrenoceptor blocking agent with a pA2 of 9.23+/-0.25 on isolated trachea. 2 It provokes hypertension in normotensive rats and does not prevent arterial hypertension in SHR rats, although it does prevent the renin secretion normally induced by isoprenaline infusion.


Jan 1, 1975·Naunyn-Schmiedeberg's Archives of Pharmacology·J L Willems, M G Bogaert
Jul 1, 1970·European Journal of Pharmacology·B Levy, B E Wilkenfeld
Mar 1, 1972·Canadian Journal of Physiology and Pharmacology·D RegoliE Gysling
Jun 1, 1946·British Journal of Pharmacology and Chemotherapy·G S DAWES


Dec 1, 1977·Naunyn-Schmiedeberg's Archives of Pharmacology·E Holmberg, B Waldeck
Jan 1, 1984·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·C J SchmittN N Share
Dec 1, 1978·European Journal of Pharmacology·C D Nicholson, K J Broadley
Jan 8, 1982·European Journal of Pharmacology·B Ek, B Lundgren
Sep 2, 1983·European Journal of Pharmacology·N L Brown, M Worcel
Aug 29, 1989·European Journal of Pharmacology·F De PaermentierR W Horton
May 1, 1987·Pharmacology, Biochemistry, and Behavior·H Frances, P Simon
Jan 1, 1987·Pharmacology, Biochemistry, and Behavior·H FrancesP Simon
Apr 1, 1993·Pharmacology, Biochemistry, and Behavior·R A Bassani, J W Bassani
Jan 1, 1989·Pharmacology & Therapeutics·M F Sugrue
Jan 1, 1979·General Pharmacology·R E Buckingham, T C Hamilton
Sep 1, 1981·Acta Physiologica Scandinavica·J Hillman, J Lundvall
Mar 25, 2014·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Hazem A GhabbourMohamed M El-Kerdawy
Jan 1, 1982·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·H C Innemee, P A van Zwieten
Apr 15, 1980·Klinische Wochenschrift·K A MeurerA Helber
Dec 1, 1980·Proceedings of the National Academy of Sciences of the United States of America·J A Nathanson
Jan 1, 1982·Clinical and Experimental Hypertension. Part A, Theory and Practice·J D Fitzgerald
Nov 1, 1983·British Journal of Clinical Pharmacology·J StaessenA Amery
Dec 1, 1982·The British Journal of Ophthalmology·G E Trope, B Clark
Dec 1, 1983·Scandinavian Journal of Clinical and Laboratory Investigation·K GrongJ Lekven
Jan 1, 1982·Acta Medica Scandinavica. Supplementum·H MattssonE Carlsson
Nov 1, 1980·Acta Pharmacologica Et Toxicologica·S B Ross
Sep 1, 1983·The Journal of Pharmacy and Pharmacology·B CostinJ C Wanstall
Apr 1, 1981·The Journal of Pharmacy and Pharmacology·S R O'Donnell, K Walduck
Apr 1, 1984·Acta Pharmacologica Et Toxicologica·R KlysnerK Winther
Dec 1, 1982·Naunyn-Schmiedeberg's Archives of Pharmacology·H MattssonT Olsson

Related Concepts

Adrenergic beta-Antagonists
Topical anesthetic
Cardiac Depressants
Diastolic Blood Pressure
Canis familiaris
Cavia porcellus
Pulse Rate

Related Feeds

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.