A potential regulatory region near the EDN3 gene may control both harness racing performance and coat color variation in horses

Physiological Reports
K Jäderkvist FegraeusG Lindgren

Abstract

The Swedish-Norwegian Coldblooded trotter and the heavier North-Swedish draught horse both descend from the North-Swedish horse, but the Coldblooded trotters have been selected for racing performance while the North-Swedish draught horse is mainly used for agricultural and forestry work. By comparing the genomes of Coldblooded trotters, North-Swedish draught horses and Standardbreds for a large number of single-nucleotide polymorphisms (SNPs), the aim of the study was to identify genetic regions that may be under selection for racing performance. We hypothesized that the selection for racing performance, in combination with unauthorized crossbreeding of Coldblooded trotters and Standardbreds, has created regions in the genome where the Coldblooded trotters and Standardbreds are similar, but differ from the North-Swedish draught horse. A fixation index (Fst) analysis was performed and sliding window Delta Fst values were calculated across the three breeds. Five windows, where the average Fst between Coldblooded trotters and Standardbreds was low and the average Fst between Coldblooded trotters and North-Swedish draught horses was high, were selected for further investigation. Associations between the most highly ranked SNPs and ...Continue Reading

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Citations

Nov 30, 2020·Journal of Animal Breeding and Genetics = Zeitschrift Für Tierzüchtung Und Züchtungsbiologie·Anne Ricard, Arnaud Duluard
Oct 17, 2020·Journal of Equine Science·Ivana Louise Santos SilvaGregório Miguel Ferreira DE Camargo
Feb 20, 2021·Journal of Applied Genetics·Gleb Strauss Borges JunqueiraRaphael Bermal Costa

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