PMID: 374571Jan 1, 1979Paper

A practical application of computer pattern recognition research: the Abbott ADC-500 differential classifier

The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society
J E Green

Abstract

The ADC-500 is a new blood cell differential classifier manufactured by Abbott Laboratories. It performs 500-cell leukocyte differentials on both normal and abnormal cells, evaluates red cell morphology and estimates platelet sufficiency at a rate of 40 to 50 samples per hour in stand-alone operation. The ADC-500 system consists of a spinner which prepares a uniform blood monolayer on a slide, a stainer which reproducibly stains the slide with Wright's stain, an encoder which attaches an instrument and human readable identification to the slide and an analyzer which accepts a stack of up to 50 slides, evaluates these slides and prints the results and the slide identification on report forms. The system's analysis rate, which represents a 5- to 10-fold increase over other commercially available differential counters, requires a number of specialized techniques for its realization. One key to this performance is the development of a high speed X-Y slide positioning stage which can move to a new cell and settle in 50 msec. Another is the high degree of parallelism used in the system structure and the pipelining of the data processing. A third is the development of uniform and repeatable sample preparation modules. Within the analy...Continue Reading

Citations

Feb 24, 1988·Journal of Immunological Methods·E StarkR Von der Fecht
Apr 6, 2002·Clinics in Laboratory Medicine·Noriyuki Tatsumi, Robert V Pierre
Jul 1, 1986·Cytometry·H M AusW Abmayr

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