A practical exposure-equivalent metric for instrumentation noise in x-ray imaging systems.

Physics in Medicine and Biology
Girijesh YadavaDaniel R Bednarek

Abstract

The performance of high-sensitivity x-ray imagers may be limited by additive instrumentation noise rather than by quantum noise when operated at the low exposure rates used in fluoroscopic procedures. The equipment-invasive instrumentation noise measures (in terms of electrons) are generally difficult to make and are potentially not as helpful in clinical practice as would be a direct radiological representation of such noise that may be determined in the field. In this work, we define a clinically relevant representation for instrumentation noise in terms of noise-equivalent detector entrance exposure, termed the instrumentation noise-equivalent exposure (INEE), which can be determined through experimental measurements of noise-variance or signal-to-noise ratio (SNR). The INEE was measured for various detectors, thus demonstrating its usefulness in terms of providing information about the effective operating range of the various detectors. A simulation study is presented to demonstrate the robustness of this metric against post-processing, and its dependence on inherent detector blur. These studies suggest that the INEE may be a practical gauge to determine and compare the range of quantum-limited performance for clinical x-ra...Continue Reading

References

Jul 1, 1995·Medical Physics·C E MetzK J Myers
Jan 1, 1997·Physics in Medicine and Biology·M J Yaffe, J A Rowlands
Mar 9, 1999·Journal of the Optical Society of America. A, Optics, Image Science, and Vision·A E Burgess
Apr 28, 2001·Physics in Medicine and Biology·N W MarshallA R Lecomber
Aug 9, 2003·Medical Physics·Giovanni BorasiDavide Tassoni
Sep 1, 1953·Journal of the Optical Society of America·A ROSE
Dec 6, 2003·Medical Physics·Arundhuti GangulyIacovos S Kyprianou
Dec 6, 2003·Medical Physics·Arundhuti GangulyKenneth R Hoffmann
Sep 5, 2006·IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society·Hilda Faraji, W James MacLean
Dec 2, 2006·Proceedings - Society of Photo-Optical Instrumentation Engineers·Stephen RudinDaniel R Bednarek
Jan 1, 2005·Proceedings - Society of Photo-Optical Instrumentation Engineers·Girijesh K YadavaKenneth R Hoffmann
Jan 1, 2005·Proceedings - Society of Photo-Optical Instrumentation Engineers·Ye WuDaniel R Bednarek

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Citations

Jun 6, 2009·The New Phytologist·Viktor ŽárskýMichal Hála
Jul 23, 2015·Biophysical Journal·Megha Rajendran, Lawrence W Miller
Dec 20, 2013·Physics in Medicine and Biology·A SisniegaJ J Vaquero
Mar 10, 2018··J. Michael YuPieter G. Roos

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