A practical rule for optimal flows for xenon anaesthesia in a semi-closed anaesthesia circuit

European Journal of Anaesthesiology
Anna B RoehlMarc Hein

Abstract

Stable haemodynamics and its cardioprotective and neuroprotective properties favour xenon as an ideal but expensive anaesthetic agent. The aim of this study was to optimize a semi-closed anaesthesia circuit for xenon anaesthesia with respect to economics and patient safety. A semi-closed nonrebreathing circuit was compared with a closed anaesthesia circuit. In 12 landrace pigs, we compared eight different wash-in procedures affecting xenon consumption. Additionally, the maintenance of anaesthesia was analysed with regard to minimizing xenon consumption. The current study showed that, by optimization of the electronic regulation of the wash-in procedure for xenon anaesthesia, the consumption of the valuable gas can be reduced by up to 75% in a semi-closed circuit. The additional maintenance of anaesthesia under low flow conditions by coupling the xenon flow to the oxygen consumption is the most effective way to technically reduce the amount of xenon needed for anaesthesia.

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Oct 26, 2007·Anesthesia and Analgesia·John Dingley, Rod S Mason
Oct 9, 2008·Acta Anaesthesiologica Scandinavica·M HeinR Rossaint
Nov 21, 2008·Anesthesia and Analgesia·Nina C WeberBenedikt Preckel

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Citations

Jun 14, 2013·Medical Gas Research·Christian StoppeMark Coburn
Feb 7, 2018·Journal of Anesthesia·Hai-Bo DengShi-Yuan Xu
Mar 26, 2015·International Anesthesiology Clinics·Galina Korsunsky
Aug 28, 2012·European Journal of Anaesthesiology·Stuart D FaulknerNicola J Robertson
Feb 26, 2020·Intensive Care Medicine Experimental·Roehl AnnaCoburn Mark

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