A Prebiotic Chemistry Experiment on the Adsorption of Nucleic Acids Bases onto a Natural Zeolite

Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life
Pedro R AnizelliDimas A M Zaia

Abstract

There are currently few mechanisms that can explain how nucleic acid bases were synthesized, concentrated from dilute solutions, and/or protected against degradation by UV radiation or hydrolysis on the prebiotic Earth. A natural zeolite exhibited the potential to adsorb adenine, cytosine, thymine, and uracil over a range of pH, with greater adsorption of adenine and cytosine at acidic pH. Adsorption of all nucleic acid bases was decreased in artificial seawater compared to water, likely due to cation complexation. Furthermore, adsorption of adenine appeared to protect natural zeolite from thermal degradation. The C=O groups from thymine, cytosine and uracil appeared to assist the dissolution of the mineral while the NH2 group from adenine had no effect. As shown by FT-IR spectroscopy, adenine interacted with a natural zeolite through the NH2 group, and cytosine through the C=O group. A pseudo-second-order model best described the kinetics of adenine adsorption, which occurred faster in artificial seawaters.

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Citations

Oct 27, 2016·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Cristine E A CarneiroDimas A M Zaia
Feb 3, 2018·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Saúl A Villafañe-BarajasDimas A M Zaia
Mar 18, 2016·Amino Acids·Ana Paula S F FariasDimas A M Zaia
Apr 9, 2020·Origins of Life and Evolution of the Biosphere : the Journal of the International Society for the Study of the Origin of Life·Dimas A M ZaiaCássia Thaïs B V Zaia

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