A preliminary assessment of vital-signs-integrated patient-assisted intravenous opioid analgesia (VPIA) for postsurgical pain.

BMC Anesthesiology
Ban Leong SNGAlex Tiong Heng SIA

Abstract

We developed a Vital-signs-integrated Patient-assisted Intravenous opioid Analgesia (VPIA) analgesic infusion pump, a closed-loop vital signs monitoring and drug delivery system which embodied in a novel algorithm that took into account patients' vital signs (oxygen saturation, heart rate). The system aimed to allow responsive titration of personalized pain relief to optimize pain relief and reduce the risk of respiratory depression. Moreover, the system would be important to enable continuous monitoring of patients during delivery of opioid analgesia. Nineteen patients who underwent elective gynecological surgery with postoperative patient controlled analgesia (PCA) with morphine were recruited. The subjects were followed up from their admission to the recovery room/ ward for at least 24 h until assessment of patient satisfaction on the VPIA analgesic infusion pump. The primary outcome measure of incidence of oxygen desaturation showed all patients had at least one episode of oxygen desaturation (< 95%) during the study period. Only 6 (31.6%) patients had oxygen desaturation that persisted for more than 5 min. The median percentage time spent during treatment that oxygen saturation fell below 95% was 1.9%. Fourteen (73.7%) out...Continue Reading

References

Feb 1, 1994·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·R C Etches
Jan 5, 2006·American Journal of Health-system Pharmacy : AJHP : Official Journal of the American Society of Health-System Pharmacists·Ray R MaddoxBernie Colclasure
Jun 18, 2009·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Jeff R ScheinD John Doyle
Jul 16, 2011·Current Opinion in Anaesthesiology·Saravanan Ankichetty, Frances Chung
Aug 10, 2011·Anaesthesia and Intensive Care·P E MacintyreD A Scott

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Citations

May 2, 2021·Clinical and Translational Medicine·Rayhan A LalEric A Appel

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Methods Mentioned

BETA
sedation
PCA
hysterectomy

Clinical Trials Mentioned

NCT02804022

Software Mentioned

SAS

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