A preliminary controlled evaluation of the antihypertensive effect of indapamide

Current Medical Research and Opinion
P TurnerH J Rogers

Abstract

A controlled, single-blind trial was carried out in 10 hypertensive patients to compare the effectiveness of a single daily dose (2.5 mg to 5 mg) of indapamide with that of placebo. Blood pressure was measured with a bias-free sphygmomanometer. Indapamide produced a significant reduction in mean systolic and diastolic pressures in both supine and erect positions. It was generally well tolerated: few side-effects were reported and no significant changes were noted in laboratory tests. It is concluded that further long-term studies of indapamide are indicated in larger numbers of patients.

References

Jan 1, 1975·Current Medical Research and Opinion·P Y Hatt, J B Leblond
Dec 1, 1973·European Journal of Clinical Pharmacology·I Persson, J Ulrich

Citations

Jan 1, 1984·Current Medical Research and Opinion·Z RumboldtM Jurisic

Related Concepts

Antihypertensive Agents
Diastolic Blood Pressure
Clinical Trials
Depression, Chemical
Diuretic Effect
Hypertensive Disease
S-1520

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