A preliminary controlled evaluation of the antihypertensive effect of indapamide

Current Medical Research and Opinion
P TurnerH J Rogers


A controlled, single-blind trial was carried out in 10 hypertensive patients to compare the effectiveness of a single daily dose (2.5 mg to 5 mg) of indapamide with that of placebo. Blood pressure was measured with a bias-free sphygmomanometer. Indapamide produced a significant reduction in mean systolic and diastolic pressures in both supine and erect positions. It was generally well tolerated: few side-effects were reported and no significant changes were noted in laboratory tests. It is concluded that further long-term studies of indapamide are indicated in larger numbers of patients.


Jan 1, 1975·Current Medical Research and Opinion·P Y Hatt, J B Leblond
Dec 1, 1973·European Journal of Clinical Pharmacology·I Persson, J Ulrich


Jan 1, 1984·Current Medical Research and Opinion·Z RumboldtM Jurisic

Related Concepts

Antihypertensive Agents
Diastolic Blood Pressure
Clinical Trials
Depression, Chemical
Diuretic Effect
Hypertensive Disease

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.