A preliminary study of the effect of essential oils on skeletal and smooth muscle in vitro

Journal of Ethnopharmacology
M Lis-Balchin, S Hart

Abstract

The pharmacological activity of nine commercial essential oils was studied on the rat isolated phrenic nerve diaphragm preparation and compared with activity on field-stimulated guinea-pig ileum preparations. The essential oils at final bath concentrations of 2 x 10(-5) and 2 x 10(-4) g/ml produced four different effects on skeletal muscle, whilst only a contracture with or without a decrease in response to field stimulation in smooth muscle. The first type of effect on skeletal muscle involved a contracture and inhibition of the twitch response to nerve stimulation shown by a sample of clary sage, dill, fennel, frankincense and nutmeg; a second, shown by thyme produced a contracture without a change in the twitch response; a third, shown by lavender reduced the twitch response alone and the fourth, shown by camphor, increased the size of the twitch response. Angelica root oil at the highest concentration studied showed no response on skeletal muscle.

References

May 1, 1990·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·R L BronaughR Sarason
Feb 1, 1981·Planta medica·C O Van den Broucke, J A Lemli
Nov 17, 1995·Journal of Ethnopharmacology·A A AlbuquerqueJ H Leal-Cardoso
Mar 1, 1946·British Journal of Pharmacology and Chemotherapy·E BULBRING

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Citations

Sep 2, 2008·Journal of Ethnopharmacology·Linfang HuangShilin Chen
Sep 7, 2004·Journal of Advanced Nursing·Wendy Maddocks-Jennings, Jenny M Wilkinson
Aug 15, 2012·Fundamental & Clinical Pharmacology·Ariane Leite Rozza, Cláudia Helena Pellizzon
Sep 15, 2004·Journal of Herbal Pharmacotherapy·Ethan BaschCatherine Ulbricht
Apr 21, 2009·Natural Product Reports·Bhahwal Ali ShahSubhash Chandra Taneja
Aug 31, 2002·Phytotherapy Research : PTR·M Lis-BalchinB Wan Hang Lo
Feb 28, 2002·British Journal of Community Nursing·Fiona Mantle
Jul 6, 2019·BMJ Open Sport & Exercise Medicine·Daniel EngelhardSimon Annaheim
Mar 20, 2009·Journal of Athletic Training·Joseph H DykstraRobert J Baker
Nov 11, 2019·Chinese Journal of Integrative Medicine·Seyedeh-Fatemeh HekmatzadehJamshid Mohammadi

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