A preliminary study of the Six-Item Screener in detecting cognitive impairment.

Neuroscience Bulletin
Mei-Rong ChenXiao-Hong Liu

Abstract

The present retrospective study was to explore the clinical value of Six-Item Screener (SIS), which is constituted by 6 items from mini-mental status examination (MMSE), to identify cognitive impairment. A total number of 1976 patients aged over 50 years, from the Memory Clinic of Huashan Hospital were employed in a battery of neuropsychological tests including MMSE. Subjects with severe conditions, unable to cooperate, or having been previously enrolled, were excluded from this study. The employed subjects were divided into 3 groups: subjective memory complaints (SMCs) (475 cases), patients with mild cognitive impairment (MCI) (440 cases), and patients with Alzheimer's disease (AD) (1061 cases, including 555 mild, 339 moderate, and 167 severe). A total score of MMSE and a score of SIS composed of date, month, year, three-word delayed recall from MMSE were calculated. Data were analyzed based on educational background. The cut-off of SIS score was <2 for illiterate, <3 for elementary, and <4 for junior high school or above. The sensitivity and specificity of SIS for detecting mild AD were 88.5% and 78.3%, respectively, with an overall accuracy of 83.8%, while for detecting MCI, the sensitivity and specificity were 34.3% and 90....Continue Reading

References

Sep 1, 1992·Journal of the American Geriatrics Society·T N Tombaugh, N J McIntyre
Jan 1, 1990·Archives of Neurology·D GalaskoL J Thal
May 1, 1990·Annals of Internal Medicine·M S LachsM E Tinetti
Jul 1, 1985·Journal of the American Geriatrics Society·L E KleinM Folstein
Mar 10, 2001·International Journal of Geriatric Psychiatry·J Scanlan, S Borson
Jul 12, 2002·Journal of the American Geriatrics Society·Gail KuslanskyRichard B Lipton
Jul 5, 2005·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Scott T WilberLowell W Gerson
Aug 12, 2008·Academic Emergency Medicine : Official Journal of the Society for Academic Emergency Medicine·Scott T WilberFredric M Hustey
Apr 30, 2009·Dementia and Geriatric Cognitive Disorders·Laure CarcaillonJean-François Dartigues

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Citations

Apr 9, 2014·Journal of Cross-cultural Gerontology·Annie L Nguyen, David W Seal
Mar 18, 2015·International Journal of Geriatric Psychiatry·Daniel ApolinarioSonia Maria Dozzi Brucki
May 23, 2012·American Journal of Obstetrics and Gynecology·Karen L Miller, Carole A Baraldi
Mar 31, 2018·Physiotherapy Theory and Practice·Adam RufaMichelle Dolphin
Apr 18, 2015·International Psychogeriatrics·Xiangliang ChenXinfeng Liu
Jan 11, 2020·Frontiers in Psychiatry·José Wagner Leonel Tavares-JúniorPedro Braga-Neto
Mar 17, 2021·Brazilian Journal of Physical Therapy·Isabella de Oliveira NascimentoRaquel Rodrigues Britto
Aug 11, 2021·Journal of the International Neuropsychological Society : JINS·Wei Gabriel QiYue Hong

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