A preliminary study on sentinel lymph node biopsy: feasibility and predictive ability in oral cavity cancer

Annals of Nuclear Medicine
Kazuaki ChikamatsuNobuhiko Furuya

Abstract

The main factor that affects the prognosis of patients with head and neck cancer (HNC) is regional lymph node metastases. For this reason, the accurate evaluation of neck metastases is required for neck management. This study investigates the sentinel lymph node identification and the accuracy of the histopathology of the sentinel lymph node in patients with HNC. Eleven patients with histologically proven oral squamous cell carcinoma accessible to radiocolloid injection were enrolled in this study. Using both lymphoscintigraphy and a handheld gamma probe, the sentinel lymph node could be identified in all 11 patients. Subsequently, the sentinel lymph nodes and the neck dissection specimen were examined for lymph node involvement due to tumor. The histopathology of sentinel lymph nodes was consistent with the pathological N classification in all 11 patients. Furthermore, the histopathology of sentinel lymph nodes was superior to physical examination, computed tomography (CT), magnetic resonance imaging (MRI) and positron emission tomography (PET) scan. The results of this study indicate that sentinel lymph node identification is technically feasible and predicts cervical metastases in patients with oral cavity cancer. This may b...Continue Reading

References

Apr 1, 1992·Archives of Surgery·D L MortonA J Cochran
Sep 1, 1995·Annals of Surgery·A E GiulianoD L Krasne
Apr 29, 1998·Archives of Otolaryngology--head & Neck Surgery·W M KochJ R Saunders
Jul 24, 1998·Archives of Otolaryngology--head & Neck Surgery·K T PitmanE N Myers
May 4, 2000·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·R P ZitschA Singh
Sep 5, 2001·Archives of Otolaryngology--head & Neck Surgery·R J TaylorD B Chepeha
Mar 12, 2002·Archives of Otolaryngology--head & Neck Surgery·Susan A EicherAnn M Gillenwater
Mar 12, 2002·Archives of Otolaryngology--head & Neck Surgery·Snehal G PatelDennis H Kraus
Sep 17, 2002·ORL; Journal for Oto-rhino-laryngology and Its Related Specialties·Christian von BuchwaldGary Ross
Sep 17, 2002·British Journal of Cancer·J A WernerTh Behr
Sep 26, 2002·The Annals of Otology, Rhinology, and Laryngology·Luigi BarzanMaria Gabriella Savignano

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Citations

Jul 10, 2009·Annals of Nuclear Medicine·Ramin SadeghiSeyed Rasoul Zakavi
Apr 20, 2005·World Journal of Surgical Oncology·K Harish
Jan 29, 2009·World Journal of Surgical Oncology·Stephen P PovoskiEdward W Martin
Mar 19, 2014·Current Oncology Reports·Marcus M Monroe, Stephen Y Lai
Sep 29, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Lee W T AlkureishiUNKNOWN European Sentinel Node Biopsy Trial Committee
Oct 2, 2009·Annals of Surgical Oncology·L W T AlkureishiUNKNOWN European Sentinel Node Biopsy Trial Committee
Dec 25, 2012·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·C F ThompsonA H Mendelsohn
Jul 6, 2010·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Nikolaos KolomvosAngelos P Angelopoulos
Mar 6, 2007·Surgical Oncology Clinics of North America·Adorján F Kovács
Dec 20, 2007·Oral and Maxillofacial Surgery Clinics of North America·Joseph M AulinoJason L Shipman
Jul 10, 2007·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Jørn Bo ThomsenAnnelise Krogdahl
Dec 1, 2007·Journal of Surgical Oncology·Anne-Sophie BatsFabrice Lécuru
Nov 20, 2019·Indian Journal of Otolaryngology and Head and Neck Surgery : Official Publication of the Association of Otolaryngologists of India·Shikharani PatelNita Khurana

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