A preliminary study: The sequential use of the risk malignancy index and contrast-enhanced ultrasonography in differential diagnosis of adnexal masses

Medicine
Li QiuHong Luo

Abstract

The aim of this study was to explore the sequential use of risk malignancy index (RMI) combined with contrast-enhanced ultrasonography (CEUS) in identification diagnosis of adnexal masses.This study contained 2 steps: first, 151 patients were analyzed retrospectively with RMI 1, RMI 2, and RMI 3 indices; receiver operating characteristic (ROC) curves were plotted to analyze area under the curves (AUC), and then RMI cut-off value was obtained according to maximum Youden index (YI, Sensitivity + Specificity - 1) and calculating diagnostic sensitivity, specificity, positive/negative predictive value, and accuracy. Second, 151 cases were divided into 2 groups randomly (105 in study group and 46 in test group); in the study group, the lower cut-off value (LC), upper cut-off value (UC), CEUS cut-off value according to maximum YI, and then these cut-offs were validated in test group.There was no statistical significance in 3 RMI models (P = .35), and RMI1 model was established randomly for following study. When the RMI1 cut-off value was 149, the YI was maximal (0.53), and the sensitivity, specificity, positive/negative predictive value, and accuracy were 71.0%, 81.7%, 77.1%, 75.6%, and 76.2%, respectively. The LC was 15 (sensitivity ...Continue Reading

References

May 2, 2001·Gynecologic Oncology·A P ManjunathR Vani
Feb 4, 2003·Radiology·Maija-Riitta OrdénPertti P Kirkinen
Nov 24, 2004·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Henri MarretFrançois Tranquart
Nov 30, 2005·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Dirk TimmermanUNKNOWN International Ovarian Tumor Analysis Group
Feb 13, 2007·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·P O van TrappenI J Jacobs
May 28, 2008·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·D TimmermanL Valentin
Nov 3, 2009·Gynecologic Oncology·Richard G MooreRobert C Bast
Nov 20, 2009·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·A C TestaL Valentin
Jan 23, 2010·AJR. American Journal of Roentgenology·Arthur C FleischerDavid A Fishman
Mar 12, 2010·The Australian & New Zealand Journal of Obstetrics & Gynaecology·Ganendra Raj Kader Ali MohanDonald Angstetra
Jun 23, 2011·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·E VaesU Menon
Sep 13, 2011·Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association for Cancer Research, Cosponsored by the American Society of Preventive Oncology·Ben Van CalsterDirk Timmerman
Aug 10, 2012·Current Oncology·J E DodgeUNKNOWN Gynecology Cancer Disease Site Group
Oct 16, 2012·Ultrasound in Obstetrics & Gynecology : the Official Journal of the International Society of Ultrasound in Obstetrics and Gynecology·J KaijserD Timmerman
Jan 16, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·F A Chervenak, L B McCullough
Feb 24, 2015·Ultrasound in Medicine & Biology·Ying WuXia Zhao
Feb 29, 2016·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·E M J MeysT Van Gorp
Nov 11, 2016·Cellular Physiology and Biochemistry : International Journal of Experimental Cellular Physiology, Biochemistry, and Pharmacology·Zongyu LiuLimei Fan
May 18, 2017·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Laure WynantsBen Van Calster

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Citations

Sep 13, 2021·International Journal of Gynaecology and Obstetrics : the Official Organ of the International Federation of Gynaecology and Obstetrics·Ailing XuDan Yang

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Methods Mentioned

BETA
imaging technique
hysterectomy

Software Mentioned

SPSS
Histo
Scanning

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