A prevalence study of folate deficiency in a psychiatric in-patient population

Acta Psychiatrica Scandinavica
U M Skerritt

Abstract

Controlled clinical trials in the UK have shown folate deficiency in psychiatric patients, and it has been suggested that such deficiency is most likely to occur among patients with affective disorders. Studies have led to the use of folate as an adjunct to therapy in such patients. The present paper describes a preliminary investigation into the red cell folate status of psychiatric patients in a general hospital unit compared with age- and sex-matched healthy controls, using up-to-date assays and strict entry criteria and overall improved methods on previous studies. The study showed that, although there is a trend for psychiatric patients to have lower serum folate levels than controls, there is no statistically significant difference in folate levels as measured by red cell folate, a more reliable measure of folate status, between healthy controls and psychiatric patients, and all but one of the patients had normal haematological indices.

References

Apr 1, 1992·Journal of Affective Disorders·S LeeC N Chen
Aug 18, 1990·Lancet·P S GodfreyE H Reynolds
Jun 1, 1990·The British Journal of Psychiatry : the Journal of Mental Science·M W Carney
Jan 1, 1989·Progress in Neuro-psychopharmacology & Biological Psychiatry·S N Young, A M Ghadirian
Jul 1, 1989·Acta Psychiatrica Scandinavica·M T Abou-Saleh, A Coppen
Jan 1, 1986·Journal of Affective Disorders·A CoppenC Swade
Jan 1, 1986·Journal of Psychiatric Research·M T Abou-Saleh, A Coppen
Jan 1, 1985·Journal of Inherited Metabolic Disease·J V MurphyR Matalon
Oct 1, 1969·Irish Journal of Medical Science·N CallaghanP Cotter
Dec 12, 1970·British Medical Journal·R H Grant, O P Stores
Dec 1, 1971·Journal of Neurology, Neurosurgery, and Psychiatry·E H ReynoldsA L Johnson
Jan 1, 1969·Acta Psychiatrica Scandinavica·O N Jensen, O V Olesen
Jun 27, 1970·British Medical Journal·C Neubauer
May 1, 1970·The Journal of Nervous and Mental Disease·M W Carney, B F Sheffield
Aug 1, 1969·Archives of Neurology·O N Jensen, O V Olesen
Dec 2, 1967·British Medical Journal·M W Carney
Oct 18, 1980·British Medical Journal·S D ShorvonE H Reynolds
Jul 1, 1982·The British Journal of Psychiatry : the Journal of Mental Science·A Coppen, M T Abou-Saleh
May 1, 1993·Drugs·R CrellinE H Reynolds
Sep 1, 1994·Psychiatry Research·V A WessonR T Joffe

❮ Previous
Next ❯

Citations

Aug 23, 2005·Progress in Neuro-psychopharmacology & Biological Psychiatry·Jan-Willem Muntjewerff, Henk J Blom
Sep 25, 1999·Psychiatry and Clinical Neurosciences·A HerránJ L Vázquez-Barquero
Sep 28, 2005·Tropical Medicine & International Health : TM & IH·S I HayA J Tatem
Aug 18, 2000·Journal of Child Psychology and Psychiatry, and Allied Disciplines·A RahmanR Gater

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Progress in Neuro-psychopharmacology & Biological Psychiatry
S N Young, A M Ghadirian
The British Journal of Psychiatry : the Journal of Mental Science
B McLaughlin, A McMahon
International Journal of Psychiatry in Medicine
Vladimir Lerner, Michael Kanevsky
© 2022 Meta ULC. All rights reserved