A prevalence study of hepatitis A virus infection in a migrant community: Is hepatitis A vaccine indicated?

The Journal of Pediatrics
C M DentingerC N Shapiro

Abstract

The Advisory Committee on Immunization Practices recommends routine hepatitis A vaccination of children living in communities with high rates of hepatitis A. Rates among children living in migrant farm worker families are unknown. Participants recruited from the 1243 migrant children aged 2 to 18 years in Okeechobee County, Florida, were administered a questionnaire. A blood sample was taken for testing for antibodies to hepatitis A virus (anti-HAV), and hepatitis A vaccine was administered. Of 244 (20%) participating children, 125 (51%) were anti-HAV-positive. Seropositivity increased with age from 34% (2- to 5-year-olds) to 81% (>/=14-year-olds) (P <.0001). In multivariate analysis, age (odds ratio [OR] = 1.2/year; 95% CI = 1.1 to 1.3), having a Mexican-born father (OR = 12.2; 95% CI = 2.2 to 227.9), and age on moving to the United States (OR = 1.3/year; 95% CI = 1.0 to 1.6) were independently associated with anti-HAV positivity. Among US-born children aged 2 to 5 years who had never left the United States, 33% were anti-HAV-positive. Anti-HAV prevalence among migrant children in Okeechobee County, including the youngest US-born children, is high, indicating ongoing transmission of HAV. Children in this and other US migrant c...Continue Reading

Citations

Jun 24, 2006·European Journal of Public Health·P BonanniUNKNOWN EUROHEP.NET Team
May 6, 2006·Emerging Themes in Epidemiology·Brian D Gushulak, Douglas W MacPherson
Jan 1, 2006·Journal of Agromedicine·Bernward SteinhorstMichael F Rotondo
Oct 3, 2002·Annual Review of Public Health·Don Villarejo
Dec 25, 2002·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Philip Rosenthal
Jul 27, 2007·Journal of Immigrant and Minority Health·Susan A SkullBeverley-Ann Biggs
Jan 27, 2012·Maternal and Child Health Journal·Zeynep SimsekNebiye Yentür Doni

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