A proof-of-principle study comparing barrier function and cell morphology in face and body skin

International Journal of Cosmetic Science
Mihaela GorceaD Moore

Abstract

The purpose of this pilot in vivo study was to investigate corneocyte size and transepidermal water loss (TEWL) in facial cheek and volar forearm skin as a function of consecutive tape stripping. Changes in corneocyte size and transepidermal water loss (TEWL) were measured as a function of stratum corneum (SC) depth at both anatomical sites. To our knowledge, this is the first published quantitative comparison based on these parameters. This work complements our previously published studies on face skin barrier recovery at 24 h and 4 weeks post-tape stripping [Gorcea et al., Skin Res. Technol., 19, 2013, e375-e382; Gorcea et al., Int. J. Cosmet. Sci. 35, 2013, 250]. Transepidermal water loss in vivo measurements of forearm and facial skin sites were taken before tape stripping commenced (baseline) and after each tape was collected. Optical microscopy and image analysis techniques were employed to characterize corneocyte size as a function of skin depth (tape strip number) for both anatomical sites. Transepidermal water loss increased significantly from baseline with sequential tape stripping at both anatomical skin sites. Volar forearm skin required approximately three times as many tapes to 'damage' the SC barrier (arbitrarily...Continue Reading

References

Jan 1, 1970·The Journal of Investigative Dermatology·G Plewig, R R Marples
Nov 9, 2002·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Nobuo KashibuchiHachiro Tagami
Jun 20, 2007·Contact Dermatitis·Slaheddine Marrakchi, Howard I Maibach
Jul 6, 2007·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·R VoegeliT Schreier
Oct 6, 2009·International Journal of Pharmaceutics·Marta MachadoMajella E Lane
Jan 12, 2011·The British Journal of Dermatology·D MohammedM E Lane
Jun 20, 2012·Skin Research and Technology : Official Journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·Mihaela GorceaMajella E Lane
Jan 3, 2013·International Journal of Cosmetic Science·Mihaela GorceaDavid J Moore

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Citations

Dec 9, 2020·Journal of the European Academy of Dermatology and Venereology : JEADV·J G HolmS F Thomsen

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