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A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA

Arthritis and Rheumatism

Dec 2, 2009

Jason R KolfenbachV Michael Holers

Abstract

To describe a large, multicenter prospective cohort study of first-degree relatives (FDRs) of probands with rheumatoid arthritis (RA), and outline the use of such a study in investigating the natural history of RA development. A total of 1,058 FDRs, none of whom met the American College...read more

Mentioned in this Paper

Lyp1 PTPase
Autoantibodies
Family Health Status
Cyclic Peptides
C-reactive Protein Measurement
Articular System
Immunoglobulin Isotypes
Joints
Cyclic citrullinated peptide
Rheumatoid Arthritis
Paper Details
References
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  • Citations56
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Immunogenetics of Rheumatoid Arthritis

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A prospective approach to investigating the natural history of preclinical rheumatoid arthritis (RA) using first-degree relatives of probands with RA

Arthritis and Rheumatism

Dec 2, 2009

Jason R KolfenbachV Michael Holers

PMID: 19950324

DOI: 10.1002/art.24833

Abstract

To describe a large, multicenter prospective cohort study of first-degree relatives (FDRs) of probands with rheumatoid arthritis (RA), and outline the use of such a study in investigating the natural history of RA development. A total of 1,058 FDRs, none of whom met the American College...read more

Mentioned in this Paper

Lyp1 PTPase
Autoantibodies
Family Health Status
Cyclic Peptides
C-reactive Protein Measurement
Articular System
Immunoglobulin Isotypes
Joints
Cyclic citrullinated peptide
Rheumatoid Arthritis

Feeds With Similar Papers

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

Immunogenetics of Rheumatoid Arthritis

Rheumatoid arthritis is an autoimmune disease for which over 100 genetic risk loci have been identified. Genes involved in T cell receptor signalling, the JAK-STAT signalling pathway, and NF-kB signalling are enriched. Find the latest research on the immunogenetics of rheumatoid arthritis here.

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Paper Details
References
  • References40
  • Citations56
1234
  • References40
  • Citations56
12345...

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