A prospective comparative analysis of the accuracy of HistoScanning and multiparametric magnetic resonance imaging in the localization of prostate cancer among men undergoing radical prostatectomy

Urologic Oncology
Clement OrczykS S Taneja

Abstract

There is increasing interest in using imaging in the detection and localization of prostate cancer (PCa). Both multiparametric magnetic resonance imaging (mpMRI) and HistoScanning (HS) have been independently evaluated in the detection and localization of PCa. We undertook a prospective, blinded comparison of mpMRI and HS for cancer localization among men undergoing radical prostatectomy. Following approval by the institutional review board, men scheduled to undergo radical prostatectomy, who had previously undergone mpMRI at our institution, were offered inclusion in the study. Those consenting underwent preoperative HS following induction of anesthesia; mpMRI, HS, and surgical step-section pathology were independently read by a single radiologist, urologist, and pathologist, respectively, in a blinded fashion. Disease maps created by each independent reader were compared and evaluated for concordance by a 5 persons committee consisting of 2 urologists, 2 pathologists, and 1 radiologist. Logistic regression for correlated data was used to assess and compare mpMRI and HS in terms of diagnostic accuracy for cancer detection. Generalized estimating equations based on binary logistic regression were used to model concordance betwe...Continue Reading

References

Aug 8, 2006·The Journal of Urology·L M Boccon-GibodV Ravery
Sep 22, 2012·AJR. American Journal of Roentgenology·Andrew B RosenkrantzSamir S Taneja
May 11, 2013·The Journal of Urology·H Ballentine CarterAnthony L Zietman
Sep 17, 2013·Journal of Endourology·Petr MacekXavier Cathelineau
May 27, 2014·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Luciano A Favorito
Sep 25, 2014·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Alexander GreensteinNicola J Mabjeesh

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Citations

Oct 25, 2017·Current Urology Reports·James S WysockSamir S Taneja
Apr 8, 2021·World Journal of Urology·Andrey MorozovUNKNOWN collaboration between ESUT, ESUI and Uro-technology WP of the Young Academic Urologists

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